Metabolic risk factors and fertility disorders: A narrative review of the female perspective

Abstract

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Obesity and reproduction

“…Prior studies have shown that leptin receptors exist in the ovary and that leptin interferes with granulosa and theca cell steroidogenesis, folliculogenesis and oocyte maturation [6,7 ▪ ]. With the expansion of adipose tissue, leptin rises and adiponectin decreases [7 ▪ ]. This leads to dysregulation in glucose and fatty acid metabolism, which further affects the reproductive axis [7 ▪ ].…”

“…With the expansion of adipose tissue, leptin rises and adiponectin decreases [7 ▪ ]. This leads to dysregulation in glucose and fatty acid metabolism, which further affects the reproductive axis [7 ▪ ]. Adiponectin is produced by mature adipocytes, but is present at a lower systemic level in women with obesity.…”

Families formed through assisted reproductive technology: Causes, experiences, and consequences in an international context

“…Still, other risk factors related to lifestyle demand our attention, as they increase the risk of infertility independent of age. The contribution by Westerman and Kuhnt (2022, this issue) sheds light on metabolic risk factors – most importantly, obesity – as significant causes of female infertility. Since the prevalence of obesity among women is increasing, and this trend is expected to continue, the relevance of metabolic status is worth exploring.…”

A Review on Risk Management in Information Systems: Risk Policy, Control and Fraud Detection

“…Risk factors are attributed to particular factors in which their occurrence or presence increases the probability of the occurrence of negative outcomes associated with a risk event. There are many risk factors detected and discussed in different investigations within various fields (e.g., in healthcare systems [28,29]). These can be classified into ten groups, including: (1) top management support; (2) processes management; (3) involvement of end-users; (4) IS developing management; (5) requirement analysis; (6) project plan; (7) project management, monitoring, and evaluation; (8) team project management; (9) team experience management; and (10) team communication management.…”