Metabolic Parameters Affected by Feeding Various Types of Fiber to Guinea Pigs

Gc, Fahey; Bl, Miller; Hw, Hadfield

doi:10.1093/jn/109.1.77

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…2). This could be the result of a slowed transit time of digesta and/or an altered lipid metabolism associ ated with low fiber content in the diet [2,8,23]. Relatively lower body weight gains from the 34% fiber groups were possibly due to reduced energy intake.…”

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Protein and Fiber on Growth and Selected Cholesterol Responses of Rats

Park

Harrold²

1983

Ann Nutr Metab

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The effect of dietary protein and fiber on growth and metabolic parameters in blood serum, liver and kidney were determined in a 2 × 5 factorial experiment involving 40 Sprague-Dawley rats. Treatment variables were two dietary protein levels (16 and 24%) and five acid detergent fiber levels (6, 10, 16, 24 and 34%). No difference in growth rate of rats was found due to varying levels of either protein or fiber in the diet. Increasing the dietary protein level from 16 to 24% resulted in an 18.5% reduction in blood cholesterol. The dietary treatment containing 16 % fiber influenced most metabolic parameters examined, including blood serum cholesterol, liver cholesterol and total lipid content in liver and kidney. Rats receiving the diet containing 16% fiber had the highest serum cholesterol (88.9 mg/dl) and the lowest liver cholesterol (4.4 mg/g) as compared with other fiber groups.

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Section: Discussionmentioning

confidence: 99%

Effects of Dietary Protein and Fiber on Growth and Selected Cholesterol Responses of Rats

Park

Harrold²

1983

Ann Nutr Metab

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“…On all diets, the rats remained healthy. Previously reported dietary studies have mostly used pellet diets to which various dietary supplements have been added [3,10,11]. Pellets can vary in their composition and particularly in fibre content.…”

Section: Discussionmentioning

confidence: 99%

Intra-Caecal Short Chain Fatty Acids Are Altered by Dietary Pectin in the Rat

Thomsen¹,

Roberton²,

Wong³

et al. 1984

Digestion

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When Dark Agouti rats were changed from a conventional pellet diet containing 3.3% crude fibre and 4% fat to the experimental diet containing 5% pectin and 17% fat, the levels of n-butyrate in the caecum rapidly decreased more than fivefold. Such a change could be important as n-butyrate is known to be a major energy source for colonocytes, and to affect colon tumour cell development in vitro. Striking decreases in the caecal concentrations of the short chain fatty acids isobutyrate, n-valerate and isovalerate occurred when Wistar rats were fed an experimental diet containing 5 % pectin as the only dietary fibre, compared to rats fed the experimental diet containing no dietary fibre. These large changes in the short chain fatty acid profile, caused by pectin supplementation, have important implications for the metabolism and health of the colon.

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“…The composition (%) of the diet used by Fahey et a1. 10 ) was partially modified as follows and used as the basal diet: soybean extract protein instead of casein, the addition of 5% of brewers yeast, and the addition of 2% of vitamin C (twice the amount described by Fahey et at.) for the anticipated stress of sensitization.…”

Section: Methodsmentioning

confidence: 99%