Metabolic Engineering, Synthetic Biology, Biomedicine, Nanomaterials in Biotechnology Journal

Application of Nanomaterials in Stem Cell‐Based Therapeutics for Cardiac Repair and Regeneration

“…The development of nanomaterials has experienced remarkable progress in different fields of tissue regeneration, including tumor therapy, imaging, and drug delivery. [ 13–16 ] Nanomaterials usually consist of organic materials, metals, polymers, ceramics, and compound of nanoparticles (NPs), nanoclusters, nanocrystals, nanotubes, nanofibers, or 3D nanostructure morphology, [ 17–20 ] which have shown promising prospect in advancing tissue repair and regeneration. Nanostructured biomaterials have been used to improve stem cell implantation in cell‐based therapy, tissue repair, and wound dressings due to their biocompatibility, adhesion strength in tissue approximation, ability to enhance differentiation of stem cells, and biodegradability.…”

“…[8][9][10][11][12] However, there are many problems hindering the application of these approaches in clinical practice.The development of nanomaterials has experienced remarkable progress in different fields of tissue regeneration, including tumor therapy, imaging, and drug delivery. [13][14][15][16] Nanomaterials usually consist of organic materials, metals, polymers, ceramics, and compound of nanoparticles (NPs), nanoclusters, nanocrystals, nanotubes, nanofibers, or 3D Cardiovascular disease is a leading cause of disability and death worldwide. Although the survival rate of patients with heart diseases can be improved with contemporary pharmacological treatments and surgical procedures, none of these therapies provide a significant improvement in cardiac repair and regeneration.…”