Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish

Fan, Qiqi; Liang, Ruiqiang; Chen, Meilin; Li, Zhiqi; Tao, Xiaoyu; Ren, Hongmin; Sheng, Yuhan; Li, Jiaqi; Lin, Ruichao; Zhao, Chongjun; She, Gaimei

doi:10.1016/j.ecoenv.2024.116448

Ecotoxicology and Environmental Safety

2024

DOI: 10.1016/j.ecoenv.2024.116448

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Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish

Qiqi Fan,

Ruiqiang Liang,

Meilin Chen

et al.

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Autophagy and PPARs/NF-κB-associated inflammation are involved in hepatotoxicity induced by the synthetic phenolic antioxidant 2,4-di-tert-butylphenol in common carp (Cyprinus carpio)

Xie,

Yin,

Lin

et al. 2024

Ecotoxicology and Environmental Safety

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Autophagy and PPARs/NF-κB-associated inflammation are involved in hepatotoxicity induced by the synthetic phenolic antioxidant 2,4-di-tert-butylphenol in common carp (Cyprinus carpio)

Xie,

Yin,

Lin

et al. 2024

Ecotoxicology and Environmental Safety

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Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish

Cited by 1 publication

References 61 publications

Autophagy and PPARs/NF-κB-associated inflammation are involved in hepatotoxicity induced by the synthetic phenolic antioxidant 2,4-di-tert-butylphenol in common carp (Cyprinus carpio)

Autophagy and PPARs/NF-κB-associated inflammation are involved in hepatotoxicity induced by the synthetic phenolic antioxidant 2,4-di-tert-butylphenol in common carp (Cyprinus carpio)

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