Abstract:Background: Treatment of chronic hepatitis C (CHC) with direct acting antivirals (DAAS) improves the rates of sustained virological response (SVR). However, derangements with lipid profile and glycemic status have been observed. This study aimed to compare the effect of sofosbuvir/daclatasvir (SOF/DAC) versus sofosbuvir/ledipasvir (SOF/LED) regimens on metabolic status of CHC patients. Methods: An observational prospective study was conducted on a total of 140 easy-to-treat treatment-naïve genotype-4 chronic h… Show more
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