Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study

Walli-Attaei, Marjan; Rosengren, Annika; Rangarajan, Sumathy; Breet, Yolandi; Abdul-Razak, Suraya; Sharief, Wadeia Al; Alhabib, Khalid F; Avezum, Álvaro; Chifamba, Jephat; Dı́az, Rafael; Gupta, Rajeev; Hu, Bo; Iqbal, Romaina; Ismail, Rosnah; Kelishadi, Roya; Khatib, Rasha; Lang, Xinyue; Li, Sidong; López‐Jaramillo, Patricio; Mohan, Viswanathan; Oğuz, Aytekin; Palileo-Villanueva, Lia M; Połtyn–Zaradna, Katarzyna; Sreelakshmi, P R; Pinnaka, Lakshmi; Serón, Pamela; Teo, Koon K.; Verghese, Sejil T; Wielgosz, Andreas; Yeates, Karen; Yusuf, Rita; Anand, Sonia S.; Yusuf, Salim

doi:10.1016/s0140-6736(22)01441-6

Cited by 49 publications

(49 citation statements)

References 33 publications

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“…Studies have demonstrated that zinc deficiency and CVDs are more prevalent and sensitive in males than females, and zinc deficiency have a greater impact on CVDs in male rats. 55,56 Therefore, to reduce the number of animals used and experimental costs, only male animals were used in this study, which is a major limitation of the study. Future studies should be designed to take into consideration sex differences in cardiac effects of marginal zinc deficiency and their underlying molecular mechanisms.…”

Section: Limitationmentioning

confidence: 99%

Marginal zinc deficiency alters the heart proteome of rats

et al. 2023

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Section: Limitationmentioning

confidence: 99%

Marginal zinc deficiency alters the heart proteome of rats

et al. 2023

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“…Interestingly physical activity of any intensity was able to significantly reduce diastolic BP in women and systolic BP and HR in men. According to our findings, a prospective cohort study on metabolic, behavioral, and psychosocial risk factors and CVD in women compared with men from 21 high-income, middle-income, and low-income countries has found that a higher proportion of men were current or former smokers as well as more physically inactive than women [ 29 ]. The authors conclude that women had a more favorable cardiovascular risk profile than men, especially at younger ages [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Cardiovascular Risk Factors and Related Medical and Lifestyle Interventions Among Italian Cardiovascular Specialists: A Proof-of-Concept Study

Rosei

Pinto

Muiesan

et al. 2023

High Blood Press Cardiovasc Prev

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Introduction Physicians and researchers in the cardiovascular field are constantly engaged in the promotion of guidelines-directed preventive measures, but whether they are themselves adherent to the same recommendations was only sporadically examined. Aim To assess awareness of self-exposure to cardiovascular risk factors and related management among cardiovascular specialists. Methods During the National Conference of the Italian Society of Hypertension (October 2022), a pilot observational study on consecutive volunteer cardiovascular specialists was conducted. Participants underwent standard sitting and standing blood pressure (BP) measurements and answered a questionnaire regarding modifiable/non modifiable cardiovascular risk factors and related treatments. Based on self-declarations and actual measurements, BP was classified as optimal, normal, high-normal BP, and new hypertension in untreated participants, and as treated/untreated pre-existing hypertension. Controlled hypertension was defined as BP < 140/90 mmHg; age-adjusted lower targets were also applied, according to guidelines. Results In total, 62 participants (30 F, mean age 43.2 ± 14.8 years) were enrolled; 79% reported regular physical activity; 53% of women and 38% of men were on a low-salt diet. After smoke (19.4%), dyslipidemia was the second most common risk factor (17.7%), often occurring with high BP (26.3%) and left untreated (36.7%). Pre-existing hypertension (11.3%) was often uncontrolled (57.1%) and associated with non-adherence to guidelines-directed lifestyle recommendations. About one in 12 participants was unaware of having high measured BP values. Conclusions Despite the specific professional exposure, a margin for improvement in self cardiovascular risk factors awareness and management remains in this exploratory sample of cardiovascular specialists. This pilot research anticipates forthcoming, larger studies during national and international conferences. Supplementary Information The online version contains supplementary material available at 10.1007/s40292-023-00578-1.

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“…The primary outcome was a composite of major cardiovascular events, including cardiovascular death, myocardial infarction, stroke, and heart failure. It demonstrated that low diet quality was more strongly associated with cardiovascular diseases in female than in male participants, with an HR of 1.17 (95% CI 1.08–1.26) and 1.07 (0.99–1.15), respectively [ 44 ]. Therefore, our study also indicated that quantifying dietary quality with the DII can help prevent CHD in female patients.…”

Section: Discussionmentioning

confidence: 99%

Dietary Inflammatory Index and Its Association with the Prevalence of Coronary Heart Disease among 45,306 US Adults

Shi

Kong

et al. 2022

Nutrients

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Inflammation plays a pivotal in the occurrence and development of coronary heart disease (CHD). We aim to investigate the association between the Dietary Inflammatory Index (DII) and CHD in the present study. In this cross-sectional study, adult participants from the National Health and Nutrition Examination Survey (NHANES) (1999–2018) were enrolled. The social demographic information, lifestyle factors, blood biochemical measurements, dietary information, and CHD status of all the participants were systematically collected. Multivariable logistic regression was adopted to investigate the association between the risk of CHD and the DII. Besides, restricted cubic spline (RCS) analysis was used to explore whether there was a nonlinear association of the DII and CHD. Subgroup analysis stratified by sex, age, race/ethnicity, and BMI was conducted to evaluate the association of the DII and CHD among different populations. A total of 45,306 adults from NHANES (1999–2018) were included. Compared with individuals without CHD, the DIIs of the participants with CHD were significantly elevated. A positive association was observed between the DII and CHD in multivariable logistic analysis after adjusting for age, sex, race/ethnicity, education levels, smoking, drinking, diabetes, hypertension, and body mass index (BMI). Results of RCS analysis suggested a nonlinear relationship between the DII and CHD. In addition, the increment of the DII had a greater impact on female individuals compared with male individuals. The DII is closely associated with the risk of CHD. For better prevention and treatment of CHD, more attention should be paid to controlling dietary inflammation.

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Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study

Cited by 49 publications

References 33 publications

Marginal zinc deficiency alters the heart proteome of rats

Marginal zinc deficiency alters the heart proteome of rats

Prevalence of Cardiovascular Risk Factors and Related Medical and Lifestyle Interventions Among Italian Cardiovascular Specialists: A Proof-of-Concept Study

Dietary Inflammatory Index and Its Association with the Prevalence of Coronary Heart Disease among 45,306 US Adults

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