Metabolic and senescence characteristics associated with the immune microenvironment in ovarian cancer
Jian Xiong,
Yiyuan Fu,
Jiezheng Huang
et al.
Abstract:Ovarian cancer is a highly malignant gynecological cancer influenced by the immune microenvironment, metabolic reprogramming, and cellular senescence. This review provides a comprehensive overview of these characteristics. Metabolic reprogramming affects immune cell function and tumor growth signals. Cellular senescence in immune and tumor cells impacts anti-tumor responses and therapy resistance. Targeting immune cell metabolism and inducing tumor cell senescence offer potential therapeutic strategies. Howeve… Show more
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