Abstract:BackgroundMeningiomas are common brain tumors, defined by an innocent clinical course. However, some meningiomas reveal a malignant transformation and recur within a short time period regardless of their WHO grade. The current study aims to identify potential markers, which can discriminate between benign and malignant meningioma courses. MethodsFor this purpose, we profiled the metabolites of 43 patients with low- and high-grade meningiomas. Tumor specimens were analyzed by NMR analysis; 270 metabolites were … Show more
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