Metabolic Alkalosis in a Hemodialysis Patient After Ingestion of a Large Amount of an Antacid Medication

Sahani, Mandeep; Brennan, John F.; Nwakanma, Chukwuemeka; Chow, May T.; Ing, Todd S.; Leehey, David J.

doi:10.1046/j.1525-1594.2001.025004313.x

Cited by 4 publications

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References 8 publications

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“…Metabolic acidosis is commonly encountered in end-stage renal disease (ESRD) patients due to inability of kidneys to excrete daily acid load arising from metabolic reactions in the body. However, metabolic alkalosis is a rare condition in this patient population unless there is nasogastric suction, severe vomiting or alkali infusion [ 1 ]. We present a maintenance haemodialysis patient with severe metabolic alkalosis due to baking soda ingestion.…”

Section: Introductionmentioning

confidence: 99%

Baking soda induced severe metabolic alkalosis in a haemodialysis patient

Solak

Türkmen

Atalay

et al. 2009

Clinical Kidney Journal

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Metabolic alkalosis is a rare occurence in hemodialysis population compared to metabolic acidosis unless some precipitating factors such as nasogastric suction, vomiting and alkali ingestion or infusion are present. When metabolic alkalosis develops, it may cause serious clinical consequences among them are sleep apnea, resistent hypertension, dysrhythmia and seizures. Here, we present a 54-year-old female hemodialysis patient who developed a severe metabolic alkalosis due to baking soda ingestion to relieve dyspepsia. She had sleep apnea, volume overload and uncontrolled hypertension due to metabolic alkalosis. Metabolic alkalosis was corrected and the patient's clinical condition was relieved with negative-bicarbonate hemodialysis

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Section: Introductionmentioning

confidence: 99%

Baking soda induced severe metabolic alkalosis in a haemodialysis patient

Solak

Türkmen

Atalay

et al. 2009

Clinical Kidney Journal

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Die metabolische Alkalose – Diagnostik und Therapie

et al. 2008

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Severe Hypotension During Hemofiltration in an Uremic Patient with Metabolic Alkalosis

et al. 2004

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We describe a case of medication induced metabolic alkalosis in a maintenance dialysis patient who developed severe hypotension while undergoing a lactate hemofiltration procedure. A 73-year-old man with ESRD due to renovascular disease was used to ingesting up to 30 grams per day of a non-prescription medication (Effervescent granulare 250 grams, CRASTAN, Pisa Italy) consisting of sodium bicarbonate, citric acid, glucose and lemon flavor. For technical problem lactate hemofiltration was performed and thirty minutes after dialysis was started a severe symptomatic hypotension occurred (blood pressure 65/35 mmHg). Lactate hemofiltration was suspended and one-hour later standard bicarbonate dialysis was performed without any clinical problem. The different mechanisms in acidosis buffering occurring in lactate and bicarbonate hemofiltration were discussed.

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Metabolic Alkalosis in a Hemodialysis Patient After Ingestion of a Large Amount of an Antacid Medication

Cited by 4 publications

References 8 publications

Baking soda induced severe metabolic alkalosis in a haemodialysis patient

Baking soda induced severe metabolic alkalosis in a haemodialysis patient

Die metabolische Alkalose – Diagnostik und Therapie

Severe Hypotension During Hemofiltration in an Uremic Patient with Metabolic Alkalosis

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