Metabolic activity and clinical features of primary ganglioneuromas

Ganglioneuroma retroperitoneal en la infancia

“…Los ganglioneuromas presentan una tendencia a la recidiva local, sobretodo si la escisión no ha sido completa, y su potencial metastático descrito en la literatura sería explicado en todo caso por su multifocalidad 8 . Si no se extirpan, tras muchos años pueden malignizar en forma de Schwanomas malignos.…”

An Unusual Neck Swelling: Malignant Ganglioneuroma, a Rare Entity.

“…Elsewhere in the neck region they arise from the larynx, pharynx, and the hypoglossal nerve, along the length of the vagus and the intervertebral foramina and thereby extending to even the spinal cord. Ganglion cells, Schwann and stroma are the component of such tumors [4]. Though usually asymptomatic, they may sometimes cause symptoms when vital structures are compressed or when there are high levels of catecholamines.…”

“…Though usually asymptomatic, they may sometimes cause symptoms when vital structures are compressed or when there are high levels of catecholamines. Increase in catecholamine level lead to rise in levels of VMA and HMA in plasma or urine resulting in hypertension, diarrhoea, flushing, sweating, renal acidosis and other symptoms of catecholamine excess [5]. In a case report by Junli, there was only one case of multiple ganglioneuroma on one side of neck while 3 cases with bilateral neck masses over a period of 10 years.…”

Sympathetic nervous system tumors in children with opsoclonus myoclonus syndrome

“…Известно, что более низ-кое накопление или отсутствие накопления МЙБГ чаще наблюдается в образованиях с такими гисто-логическими вариантами, как ГНБ и ГН [23][24][25]. В частности, в нашем исследовании у 8 пациентов, у которых не было отмечено накопления МЙБГ, гистологический вариант был представлен более зрелыми подтипами -ГНБ и ГН.…”