2023
DOI: 10.1007/s00467-023-06072-z
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Metabolic acidosis in pediatric kidney transplant recipients

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Cited by 2 publications
(1 citation statement)
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“…We demonstrated distinct risk factors for metabolic acidosis in pediatric KTx recipients such as younger patient age, which is consistent with a recent report in a cohort of 63 pediatric KTx recipients. 22 Several studies have shown that young children require higher doses of tacrolimus to achieve target exposure. 23 , 24 Tacrolimus affects key transport proteins that are involved in acid-base homeostasis in the proximal and distal tubules, including endothelin-1 and H(+)-ATPase transport protein.…”
Section: Discussionmentioning
confidence: 99%
“…We demonstrated distinct risk factors for metabolic acidosis in pediatric KTx recipients such as younger patient age, which is consistent with a recent report in a cohort of 63 pediatric KTx recipients. 22 Several studies have shown that young children require higher doses of tacrolimus to achieve target exposure. 23 , 24 Tacrolimus affects key transport proteins that are involved in acid-base homeostasis in the proximal and distal tubules, including endothelin-1 and H(+)-ATPase transport protein.…”
Section: Discussionmentioning
confidence: 99%