Meta-Analysis of Three Randomized Trials and Nine Observational Studies Comparing Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Disease

Jang, Jae‐Sik; Choi, Kyu-Nam; Jin, Han-Young; Seo, Jeong-Sook; Yang, Tae–Hyun; Kim, Dae-Kyeong; Kim, Dong-Soo; Urm, Sang‐Hwa; Chun, Jin Ho; Kang, Soo–Jin; Park, Duk‐Woo; Lee, Seung-Whan; Kim, Young‐Hak; Lee, Cheol Whan; Park, Seong-Wook; Park, Seung‐Jung

doi:10.1016/j.amjcard.2012.06.051

Cited by 39 publications

(22 citation statements)

References 25 publications

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“…Respecto a la revascularización de las lesiones del tronco común de la coronaria izquierda, diversos estudios aleatorizados, subanálisis predefinidos y 2 metanálisis recientes 8,9 sugieren que ambas formas de revascularización pueden ser similares en cuanto a muerte total, muerte cardiovascular o infarto de miocardio. Además se observa que, mientras que la CABG incrementa el riesgo de ictus, el ICP se asocia a una mayor necesidad de revascularización durante el seguimiento.…”

Section: Revascularización En Pacientes Con Iamcestunclassified

Comentarios a la guía de práctica clínica de la ESC/EACTS 2014 sobre revascularización miocárdica

Cequier¹,

Maroto²,

Alfonso³

et al. 2015

Revista Española de Cardiología

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Section: Revascularización En Pacientes Con Iamcestunclassified

Comentarios a la guía de práctica clínica de la ESC/EACTS 2014 sobre revascularización miocárdica

Cequier¹,

Maroto²,

Alfonso³

et al. 2015

Revista Española de Cardiología

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“…The benefit of CABG on long-term mortality is debatable2; however, there is consensus that there is a definite reduction in the need for target vessel revascularisation (TVR) and lower major adverse cardiac events in patients undergoing CABG,3 making it the procedure of choice in unprotected left main disease. On the other hand, the risk of CVAs is significantly higher in those undergoing CABG compared with PCI 4…”

Section: Discussionmentioning

confidence: 99%

Successful hybrid coronary artery revascularisation in a patient with severe cerebrovascular disease: a new treatment option to minimise the risk of stroke

Challa¹,

Shaw

Pohlner

et al. 2017

BMJ Case Reports

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“…A number of meta-analyses have been published that summarize the data from clinical trial as well as registry data [36][37][38][39]. A summary of the various meta-analytic studies is displayed in Table 2.…”

Section: Meta-analytic Studies Summarizing Comparative Data On Pci Wimentioning

confidence: 99%

Stenting Versus Surgery for Significant Left Main Disease

Harskamp

Park

2015

Curr Cardiol Rep

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For decades, coronary artery bypass grafting (CABG) has been the choice of revascularization strategy for significant left main coronary artery (LMCA) disease. However, with marked technological advances in less invasive percutaneous strategies, such as drug-eluting stents, and potent adjunctive pharmacology, percutaneous coronary intervention (PCI) has been increasingly accepted as an alternative to CABG for selected cases with LMCA disease. The available evidence from randomized clinical trials and adequately sized, real-world registries suggest that hard clinical endpoints (death, myocardial infarction, or stroke) were comparable between two treatment strategies at short- and mid-term follow-up, while higher rate of repeat revascularization are observed after PCI. Current guidelines state that PCI for LMCA disease is reasonable in patients with low to intermediate anatomic complexity and those who are at increased surgical risk. Ongoing large-sized clinical trials comparing newer-generation drug-eluting stents and CABG would provide important clinical insights to guide optimal strategy for patients with significant LMCA disease in the (near) future.

show abstract

Meta-Analysis of Three Randomized Trials and Nine Observational Studies Comparing Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Disease

Cited by 39 publications

References 25 publications

Comentarios a la guía de práctica clínica de la ESC/EACTS 2014 sobre revascularización miocárdica

Comentarios a la guía de práctica clínica de la ESC/EACTS 2014 sobre revascularización miocárdica

Successful hybrid coronary artery revascularisation in a patient with severe cerebrovascular disease: a new treatment option to minimise the risk of stroke

Stenting Versus Surgery for Significant Left Main Disease

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