Meta-analysis of the frequency of intrauterine growth restriction and preterm premature rupture of the membranes in pregnant women with COVID-19

Bahrami, Reza; Schwartz, David A.; Karimi-Zarchi, Mojgan; Javaheri, Atiyeh; Dastgheib, Seyed Alireza; Ferdosian, Farzad; Noorishadkam, Mahmood; Mirjalili, Seyed Reza; Neámatzadeh, Hossein

doi:10.4274/tjod.galenos.2021.74829

“…This leads us to conclude that COVID-19 is not associated with adverse fetal outcome, as reported earlier [15]. A meta-analysis published estimates of the low incidence of IUGR (2.6%) in women infected with COVID-19 [16].…”

Section: Discussionsupporting

confidence: 81%

The Effects and Outcomes of the COVID-19 Pandemic on Pregnant Women in Kuwait

Akbar,

Al Azmi,

Husain

et al. 2023

Med Princ Pract

0

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Objectives: This retrospective study reports the effects of COVID-19 among hospitalized pregnant women infected with COVID-19 and compares them to a control group. Methods: We performed a multicenter retrospective cohort study, in which data of pregnant women with COVID-19, admitted to five different hospitals in Kuwait, were collected. Two groups were included; the first group was women with COVID-19 who were admitted between March 22, 2020, and December 31, 2020. The second (control) group included pregnant women without COVID-19 who were admitted between March 1, 2019, and March 21, 2020. Data were collected using a standardized data collection survey, entered using Excel software, and analyzed using analysis of variance. Results: We compared 764 patients, with confirmed COVID-19 with 765 uninfected control subjects. The majority of pregnant women were diagnosed with COVID-19 infection during the third trimester. Tachycardia was the most frequent sign at admission, and dry cough and fever were the most common presenting symptoms. ICU admission and respiratory failure were significantly higher in the COVID-19 group. Cesarean section (CS) rate was higher in the COVID-19 group, with obstetric and maternal complications being the most common indications in comparison to fetal indications in the control group. Conclusions: This study was conducted to identify the effects of COVID-19 in pregnancy. Most patients were asymptomatic. The rate of normal vaginal delivery was higher in the control group. The main indications for CS in the COVID-19 group were obstetrical and maternal complications compared to fetal complications in the control group.

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“…The risk of fetal death in utero is 5-10 times higher than that in the womb. The incidence rate is high in the perinatal period, and the risk of long-term damage is high, including poor cognitive development and postnatal cardiovascular disease defects [ 18 – 20 ]. However, with the development of life, multiple factors impact individuals, which may weaken or increase the differences observed in intrauterine and early intrauterine growth restriction [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Low-Dose Aspirin Combined with Vitamin E on the Incidence of Intrauterine Growth Restriction and Hemorheological Indexes of Pregnant Women in Patients with Gestational Hypertension

Shan

¹

,

Wang

²

,

Fang

³

2022

Computational and Mathematical Methods in Medicine

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Objective. To investigate the effect of low-dose aspirin combined with vitamin E on the incidence of intrauterine growth restriction and hemorheological indexes of pregnant women in patients with gestational hypertension. Method. 134 elderly patients with chronic urticaria treated in our hospital from November 2017 to November 2020 were studied. According to the treatment methods, they were randomly divided into observation and control groups. There were 67 patients in the observation group, aged 20-37 years, with an average of ( 25.7 ± 2.75 ) years. There were 67 patients in the control group, aged 21-35 years, with an average of ( 26.3 ± 3.17 ) years. No significant difference was observed between the two groups ( P > 0.05 ). Results. The number of cases with postpartum hemorrhage and intrauterine growth restriction in the observation group was less than that in the control group. The total incidence rate was lower than that in the control group. There were significant differences in the above results ( P < 0.05 ). The number of patients with preterm birth in the observation group was less than that in the control group, but there was no significant difference in the results ( P > 0.05 ). The head circumference, abdominal circumference, biparietal diameter, and femoral length diameter in the control and observation groups increased significantly after treatment ( P < 0.05 ). Compared with the control group, the head circumference, abdominal circumference, biparietal diameter, and femoral diameter in the observation group increased more after treatment, and the results were statistically poor ( P < 0.05 ). The systolic blood pressure, diastolic blood pressure, and mean arterial pressure in the control and observation groups decreased significantly after treatment, and the results were statistically different ( P < 0.05 ). Compared with the control group, the systolic blood pressure, diastolic blood pressure, and mean arterial pressure in the observation group decreased more after treatment. The results were statistically different ( P < 0.05 ). The plasma viscosity levels, whole blood high shear viscosity, and whole blood low shear viscosity in the control and observation groups decreased significantly after treatment, and the results were statistically different ( P < 0.05 ). Compared with the control group, plasma viscosity levels, whole blood high shear viscosity, and whole blood low shear viscosity in the observation group decreased more after treatment, and the results were statistically different ( P < 0.05 ). The control and observation groups’ fetal systolic/diastolic pressure and pulsatile index decreased significantly after treatment, and the results were statistically different ( P < 0.05 ). Compared with the control group, the fetal systolic/diastolic blood pressure and pulsatile index in the observation group decreased more after treatment, and the results were statistically poor ( P < 0.05 ). Conclusion. Low-dose aspirin combined with vitamin E is effective in treating intrauterine growth restriction in patients with gestational hypertension. It can effectively control the blood pressure and blood flow of patients and newborns and improve pregnancy outcomes without increasing the incidence of adverse reactions. It is worthy of clinical promotion.

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“…in contrast to this there was 19.5% rate of preterm deliveries in our study population and only 1.39% women died during labor. In a metanalysis other complications like fetal distress (1.1%), placenta previa (0.4%) and gestational diabetes (4.5%) [17]. Zhang et al in his study proved that the risk of complications like fetal growth restriction, placental abnormalities, neonatal asphyxia and post partum bleeding were not increased in women with COVID-19 [18].…”

Section: Discussionmentioning

confidence: 99%

Frequency and Fetomaternal Outcome in COVID 19 Positive Pregnant Women

Younus

¹

,

Naz

²

,

Hira

³

et al. 2021

JPRI

0

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Objective: To determine the frequency and outcome in pregnant women with COVID-19 infection. Study Design: This is a observational cohort study. Setting: Study carried out at Department of Obstetrics & Gynecology, Civil Hospital, Dow University of health sciences Karachi, from July 2020 to November 2021. Materials & Methods: The study was conducted in a tertiary care hospital in Karachi. Women having COVID-19 positive status during any stage of their pregnancy having antenatal visits in our hospital were included in our study. Maternal demographics, race, maternal outcome, and neonatal complications were noted on a self-made Performa. Statistical analysis was done by SPSS version 21 and descriptive statistics with frequencies were mainly calculated. Results: During the defined time of 14 months, we had 143 women visiting antenatal outpatient department and were tested positive for COVID-19. Majority of the women were tested for COVID-19 due to symptoms like fever, flu, cough and diarrhea. The mean age of women in our study was found to be 30 ± 6.7 years. The most frequent maternal outcome with SARSCOV-2 was preterm delivery. Out of 143, 27 cases had emergency lower segment C-section.PCR testing of neonates was carried out and 8.39% (n=12) neonates tested positive for SARSCOV-2. Conclusion: Infection with Covid-19 during pregnancy is associated with adverse pregnancy outcomes. Covid-19 infection can be transmitted to the fetus during pregnancy or childbirth. Neonatal has a high chance of being admitted to the ICU, and women also faces other complications of Covid 19, such as the risk of miscarriage and premature delivery.

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Meta-analysis of the frequency of intrauterine growth restriction and preterm premature rupture of the membranes in pregnant women with COVID-19

Cited by 13 publications

References 0 publications

The Effects and Outcomes of the COVID-19 Pandemic on Pregnant Women in Kuwait

The Effects and Outcomes of the COVID-19 Pandemic on Pregnant Women in Kuwait

Effects of Low-Dose Aspirin Combined with Vitamin E on the Incidence of Intrauterine Growth Restriction and Hemorheological Indexes of Pregnant Women in Patients with Gestational Hypertension

Frequency and Fetomaternal Outcome in COVID 19 Positive Pregnant Women

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