Meta-analysis of the effect of sarcopenia in predicting postoperative mortality in emergency and elective abdominal surgery

The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis

“…The prognostic influence of sarcopenia in surgical patients has received great attention in recent years, as attested by the profusion of articles and meta-analyses carried out investigating this relation[ 44 – 46 ]. Hajibandeh et al (2019) analyzed the effect of sarcopenia on postoperative mortality in patients undergoing emergency abdominal surgeries, identifying longer hospital stays, greater need for an ICU, and increased mortality within 30 days (RR 2.15) and 1 year after surgery (RR 1.97)[ 45 ]. The presence of sarcopenia was also associated with increased length of hospital stay after pancreatic surgery in the meta-analysis by Ratnayake et al [ 46 ], although a higher risk of postoperative complications has not been identified, which was partially attributed to the heterogeneity of the data.…”

“…Lanza et al (2020) investigated patients undergoing bland transarterial embolization for unresectable hepatocellular carcinoma and found out that sarcopenia can be used as a predictor of survival, with an HR = 2.22 for reduced survival[ 44 ]. However, the majority of these studies used the term “sarcopenia” considered only reduction of muscle mass evaluated by tomography [ 45 – 47 ]. In specific populations, such as cirrhotic patients in a transplant waiting list, there are studies that have diagnosed sarcopenia by associating a measure of muscle strength with a measure of muscle mass—for example, handgrip strength assessed by dynamometer and image assessed by DEXA [ 48 ].…”

The Need for Accurate Risk Assessment in a High-Risk Patient Population: A NSQIP Study Evaluating Outcomes of Cholecystectomy in the Patient With Cancer

“…21 Similarly, abnormalities in BMI, including both obesity and sarcopenia, are associated with increased rates of surgical site infection and postoperative mortality in patients undergoing abdominal surgery. 22,23 Matching was performed using the nearest-neighbor approach. Inclusion criteria included: cholecystectomy listed as the primary Current Procedural Terminology (CPT) code and diagnosis of disseminated cancer or evidence of having received recent chemotherapy.…”

Protein Requirements in Critical Illness: Do We Really Know Why to Give So Much?

“…35 Moreover, sarcopenic obesity is an independent predictor of mortality. 36,37 Unfortunately, sarcopenia cannot be predicted by BMI or nutrition assessment scores, which makes difficult to calculate protein requirements based on BMI or scores. 38,39 In protein-requirement calculation, we should mention that muscle catabolism is more pronounced in multiple-organ failure than in single-organ failure, 40 but more protein provision in multiple-organ failure (including renal and hepatic failure) can worsen outcomes.…”

“…Sarcopenia negatively impacts short‐term outcomes in patients undergoing hepatic resection for colorectal liver metastasis and repair of aortic aneurysm . Moreover, sarcopenic obesity is an independent predictor of mortality …”