Meta‐analysis of the demographic and prognostic significance of right‐sided versus left‐sided acute diverticulitis

Hajibandeh, Shahab; Smart, Neil; Maw, Andrew

doi:10.1111/codi.15328

Cited by 12 publications

(16 citation statements)

References 23 publications

(76 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the current study, the location of diverticulitis was an independent risk factor for its recurrence among Asian patients. Although acute diverticulitis was more common on the right-sided colon, this location presented a relatively minor risk for recurrence and favorable outcomes 16 . In contrast, patients with diverticulitis in the sigmoid colon and descending colon had a higher risk of recurrence.…”

Section: Discussionmentioning

confidence: 97%

Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients

Sung

Liu

Wang

et al. 2022

Sci Rep

View full text Add to dashboard Cite

Evidence regarding the recurrence of diverticulitis is limited in Asian patients. This study aims to investigate recurrence rates and identify predictive factors for the recurrence of diverticulitis following successful nonoperative treatment in Asian patients. A multicenter, retrospective cohort study was conducted between 2012 and 2018. Adult patients with computed tomography (CT)-proven colonic diverticulitis were included. The primary outcome was the recurrence of diverticulitis, which was defined as another episode of occurrence of the infection after index hospital stay. Cumulative recurrence rates were calculated using the Kaplan–Meier method. Cox regression models were employed to identify parameters that significantly and independently predicted recurrence. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated. A total of 929 patients were included. Diverticulitis in the cecum/ascending occurred in 675 (72.6%) patients. The average follow-up period was 651 days. Recurrence was observed in 115 (12.4%) patients and most significantly observed in patients with sigmoid diverticulitis (HR, 2.24; 95% CIs 1.59–3.97), followed by those with descending colon diverticulitis (HR, 1.92; 95% CIs 1.17–3.25). Although most of the Asian patients had right-sided colonic diverticulitis, those with sigmoid diverticulitis had the highest risk of recurrence.

show abstract

Section: Discussionmentioning

confidence: 97%

Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients

Sung

Liu

Wang

et al. 2022

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Smoking does not appear to significantly increase the risk of developing RCD [3,53]. However, the likelihood of developing right-sided AD is elevated in smokers [51] and may also increase the likelihood of complicated diverticulitis [54].…”

Section: Smokingmentioning

confidence: 95%

“…More thoroughly investigated is the influence of obesity on developing AD in patients with RCD. A recent meta-analysis addressed this, finding no association between obesity and the development of right-sided AD among 1,252 patients across 4 studies [51].…”

Section: Obesity As a Risk Factor For Right-sided Diverticulosismentioning

confidence: 99%

The Epidemiology and Etiology of Right-Sided Colonic Diverticulosis: A Review

et al. 2021

View full text Add to dashboard Cite

Diverticulosis of the colon is a common condition in Western countries and most patients will remain asymptomatic, but some will present with symptoms of acute diverticulitis or bleeding. Our understanding of diverticulosis is evolving but is mostly derived from diverticulosis affecting the left-sided colon. In contrast, right-sided colonic diverticulosis (RCD) is more commonly seen in Asian countries but is much less common overall. Based on the marked differences in epidemiology, it is commonly thought that these are 2 distinct disease processes. A review of the literature describing the epidemiology and etiology of RCD was performed, with a comparison to the current understanding of left-sided diverticulosis. RCD is becoming increasingly common. The epidemiology of RCD shows it to be a mostly acquired condition, and not congenital as previously thought. Many factors in the etiology of RCD are similar to that seen in left-sided diverticulosis, with a few variations. It is therefore likely that most cases of RCD represent the same disease process that is seen in the left colon.

show abstract

“…Further, it has a more favorable outcome with lower risk of complications, less frequent emergency surgery, recurrence, and length of hospital stay (Table 6 and 7 ). 64 , 65 …”

Section: Diverticulitismentioning

confidence: 99%

Essential updates 2020/2021: Colorectal diseases (benign)—Current topics in the surgical and medical treatment of benign colorectal diseases

Shinmoto

Miyamoto

Yoshida

et al. 2022

Annals of Gastroent Surgery

View full text Add to dashboard Cite

The development of new drugs for inflammatory bowel disease (IBD) is remarkable, and treatment strategies using multiple agents and various techniques are required; however, the treatment strategy is likely to be complex. Therefore, appropriate evaluation of traditional surgical treatment strategies and accurate knowledge of the efficacy and limitations of novel treatments are required. Total infectious complications were found to be associated with the use of corticosteroids and anti‐tumor necrosis factor‐α agents, but not with immunomodulators, anti‐integrin agents, and 5‐aminosalicylic acid. Regarding surgical procedures for IBD, conceived anastomosis methods, including Kono‐S for Crohn's disease stenosis, are associated with better outcomes than conventional techniques. Autologous cell transplantation for Crohn's fistulae has been shown to have a favorable outcome. Diverticulitis is increasing and will be treated more frequently in the future. Risk factors for the incidence of diverticulitis and differences in pathogenesis according to right or left side diverticulitis have been reported. Antibiotic therapy may be omitted for uncomplicated diverticulitis. Moreover, regarding surgical procedures, both bowel resection and anastomosis are associated with favorable short‐term outcomes, higher stoma closure rate, and superior medical economy compared to Hartmann's procedure. Risk factors for recurrence after diverticulitis surgery may provide better postoperative follow‐up. In this review, we explore the current topics of colorectal benign diseases, focusing on IBD and diverticulitis, based on clinical trials and meta‐analyses from 2020‐2021. This review consolidates the available knowledge and improves the quality of surgical procedures and perioperative management for IBD and diverticulitis.

show abstract

Meta‐analysis of the demographic and prognostic significance of right‐sided versus left‐sided acute diverticulitis

Cited by 12 publications

References 23 publications

Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients

Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients

The Epidemiology and Etiology of Right-Sided Colonic Diverticulosis: A Review

Essential updates 2020/2021: Colorectal diseases (benign)—Current topics in the surgical and medical treatment of benign colorectal diseases

Contact Info

Product

Resources

About