Meta-analysis approach to study the prevalence of chronic obstructive pulmonary disease among current, former and non-smokers

Kamal, Ritul; Srivastava, A. K.; Kesavachandran, Chandrasekharan Nair

doi:10.1016/j.toxrep.2015.07.013

Cited by 22 publications

(17 citation statements)

References 64 publications

(60 reference statements)

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“…Biologically active trace minerals (biotic agents) are essential key factors in a wide range of individual and bacterial enzymes; however, the consistent guideline for their bioavailability is necessary to avoid contamination [[94], [95], [96]]. Some previous studies in chronic bronchitis patients have confirmed higher concentrations of copper in the airway secretions and assumed this mineral may mask the severity of infection.…”

Section: Discussionmentioning

confidence: 99%

Essential trace elemental levels (zinc, iron and copper) in the biological samples of smoker referent and pulmonary tuberculosis patients

et al. 2019

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Section: Discussionmentioning

confidence: 99%

Essential trace elemental levels (zinc, iron and copper) in the biological samples of smoker referent and pulmonary tuberculosis patients

et al. 2019

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“…Smoking is linked to 80% of prevalent COPD cases in the U.S. [ 4 ]. A meta-analysis found that COPD prevalence in current smokers is about 30% higher than in former smokers [ 17 ]. However, this study included only a single smoking measure (smoking status) and was unable to provide age-specific relative risks for COPD prevalence.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, smokers could change their smoking behaviors throughout their lifetime, and these changes may affect individual COPD risk with age. Overall, better information is needed on how individual smoking histories shape age-specific COPD risk [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Prediction of COPD risk accounting for time-varying smoking exposures

Meza

Levy²,

Jeon

2021

PLoS ONE

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Rationale Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of death in the United States. Studies have primarily assessed the relationship between smoking on COPD risk focusing on summary measures, like smoking status. Objective Develop a COPD risk prediction model incorporating individual time-varying smoking exposures. Methods The Nurses’ Health Study (N = 86,711) and the Health Professionals Follow-up Study (N = 39,817) data was used to develop a COPD risk prediction model. Data was randomly split in 50–50 samples for model building and validation. Cox regression with time-varying covariates was used to assess the association between smoking duration, intensity and year-since-quit and self-reported COPD diagnosis incidence. We evaluated the model calibration as well as discriminatory accuracy via the Area Under the receiver operating characteristic Curve (AUC). We computed 6-year risk of COPD incidence given various individual smoking scenarios. Results Smoking duration, year-since-quit (if former smokers), sex, and interaction of sex and smoking duration are significantly associated with the incidence of diagnosed COPD. The model that incorporated time-varying smoking variables yielded higher AUCs compared to models using only pack-years. The AUCs for the model were 0.80 (95% CI: 0.74–0.86) and 0.73 (95% CI: 0.70–0.77) for males and females, respectively. Conclusions Utilizing detailed smoking pattern information, the model predicts COPD risk with better accuracy than models based on only smoking summary measures. It might serve as a tool for early detection programs by identifying individuals at high-risk for COPD.

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“…Tobacco consumption is one of the leading risk factors for early death and disability worldwide [1]. Continued smoking is regarded as a major risk factor in the development of severe medical conditions, such as cancer [2], pulmonary disease [3] and cardiovascular disease [4,5]. Moreover, due to productivity loss and high follow-up treatment costs, it imposes a heavy burden on the economy [6].…”

Section: Background and Rationale {6a}mentioning

confidence: 99%

Efficacy of a short-term residential smoking cessation therapy versus standard outpatient group therapy (‘START-Study’): study protocol of a randomized controlled trial

Dickreuter

Schmoor

Bengel³

et al. 2020

Trials

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Background: In Germany, evidence-based outpatient smoking cessation therapies are widely available. Long-term abstinence rates, however, are limited. Studies suggest that short-term residential therapy enables a higher level of environmental control, more intense contact and greater support among patients and from therapists, which could result in higher abstinence rates. The aim of the current START-study is to investigate the long-term efficacy of a short-term residential therapy exclusively for smoking cessation, conducted by a mobile team of expert therapists. Methods: A randomized controlled trial (RCT) is conducted to examine the efficacy of residential behavior therapeutic smoking cessation therapy compared to standard outpatient behavior therapeutic smoking cessation group therapy. Adult smokers consuming 10 or more cigarettes per day, who are willing to stop smoking, are randomized in a ratio of 1:1 between therapy groups. The primary endpoint is sustained abstinence for 6-month and 12-month periods. Secondary endpoints include smoking status after therapy, 7-day point abstinence after the 6-month and 12-month follow-ups, level of physical dependence, cost-effectiveness, use of nicotine replacement products, health-related quality of life, self-efficacy expectation for tobacco abstinence, motivational and volitional determinants of behavior change, self-reported depressive symptom severity, adverse events and possible side effects. Assessments will take place at baseline, post-therapy, and at 6-month and 12-month intervals after smoking cessation. Discussion: There is a high demand for long-term effective smoking cessation therapies. This study represents the first prospective RCT to examine the long-term efficacy of a residential smoking cessation therapy program compared to standard outpatient group therapy as an active control condition. The residential therapeutic concept may serve as a new model to substantially enhance future cessation therapies and improve the understanding of therapeutic impact factors on tobacco abstinence. Utilizing a mobile team, the model could be applied efficiently to medical centers that do not have permanent and trained personnel for smoking cessation at their disposal.

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Meta-analysis approach to study the prevalence of chronic obstructive pulmonary disease among current, former and non-smokers

Cited by 22 publications

References 64 publications

Essential trace elemental levels (zinc, iron and copper) in the biological samples of smoker referent and pulmonary tuberculosis patients

Essential trace elemental levels (zinc, iron and copper) in the biological samples of smoker referent and pulmonary tuberculosis patients

Prediction of COPD risk accounting for time-varying smoking exposures

Efficacy of a short-term residential smoking cessation therapy versus standard outpatient group therapy (‘START-Study’): study protocol of a randomized controlled trial

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