2006
DOI: 10.1093/annonc/mdl238
|View full text |Cite
|
Sign up to set email alerts
|

Meta-analyses of adjuvant therapies for women with early breast cancer: the Early Breast Cancer Trialists’ Collaborative Group overview

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

1
53
0
2

Year Published

2008
2008
2022
2022

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 89 publications
(56 citation statements)
references
References 12 publications
1
53
0
2
Order By: Relevance
“…Although the incidence of breast cancer continues to rise, mortality has declined over the past several years (1,2). The decline has been attributed to both early diagnosis and more effective treatment (2).…”
mentioning
confidence: 99%
“…Although the incidence of breast cancer continues to rise, mortality has declined over the past several years (1,2). The decline has been attributed to both early diagnosis and more effective treatment (2).…”
mentioning
confidence: 99%
“…In addition to their indisputable numerous roles in the physiology of healthy organisms, a growing body of work indicates they also represent an important pharmaceutical target in number of diseases including cancer. For instance, ER and PR are important targets in the breast cancer [2,3], while AR is the major therapeutic target in prostate tumors [4]. Ligands antagonizing natural hormone ligands for these receptors with reduced side effects are intensively sought as potential drugs for cancer treatment.…”
Section: Introductionmentioning
confidence: 99%
“…However, many breast tumors eventually develop resistance to cytotoxic chemotherapeutic agents, and tumors can recur even with the use of adjuvant therapies. [2][3][4][5][6][7][8] Ipsilateral breast tumors may recur after resection and/or radiation therapy even with adjuvant therapies. 5,9,10 When combined with surgery, therapies that target specific unregulated cell proliferation and angiogenic signaling pathways have often demonstrated improved outcomes, oftentimes with less severe side effects.…”
Section: Introductionmentioning
confidence: 99%