Abstract:BackgroundAn optimal therapeutic regimen for endometrial cancer with extra-uterine metastasis is unavailable. This study aimed to improve our understanding about the genomic landscape of advanced endometrial cancer and identify potential therapeutic targets.MethodsThe clinical and genomic profiles of 81 patients with stage III or IV endometrial cancer were integrated. The genomic landscape was compared with that of The Cancer Genome Atlas (TCGA) cohort. To identify genomic aberrations associated with clinical … Show more
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