Mesothelioma incidence in 50 states and the District of Columbia, United States, 2003–2008

Abstract

Background-The decline in asbestos use in the United States may impact mesothelioma incidence.

Mesothelioma: recent highlights

“…In spite of stringent regulations introduced in the 1970s and 1980s in the US (and other countries) to limit asbestos exposure, the incidence of mesothelioma reached 3,200 cases/year in the US in 2003 and it has remained stable since (23). The incidence of mesothelioma has also increased worldwide over the past 50 years (23).…”

“…In spite of stringent regulations introduced in the 1970s and 1980s in the US (and other countries) to limit asbestos exposure, the incidence of mesothelioma reached 3,200 cases/year in the US in 2003 and it has remained stable since (23). The incidence of mesothelioma has also increased worldwide over the past 50 years (23). A growing number of mesotheliomas, estimated at 20-50%, develop in individuals with no history of asbestos exposure suggesting that other factors cause mesothelioma or that some individuals may be very susceptible to even minimal amounts of asbestos (1,12).…”

In vitro experimental models of mesothelioma revisited

“…In the United States, for example, even though predictions suggested that the incidence of MPM should have peaked in the early 2000s (9), the incidence rate per 100,000 people, shows no change since 1975 (10). Currently, the annual incidence of MPM in the United States remains approximately 3,200 individuals affected (11). Further, the latest analysis from the Centers for Disease Control and Prevention observed that the annual number of deaths from mesothelioma continued to unexpectedly increase by 4.8% (P for linear time trend <0.001) overall to 2,579 cases in 2015.…”

Malignant Pleura Mesothelioma: Clinical Perspectives

“…In a percentage >75,1% MPM was diagnosed in ages of >65 years. [9] However, because of the prohibition of asbestos use, it is believed that the frequency of MPM in the US will decrease. [3] According to WHO, the United Kingdom (UK) follows, having 14,6% of MPM deaths worldwide.…”

“…Rarely it can arise from testicles (<1%) [6] or the pericardium (<1%) [7]. This oncological entity arises from the mesothelial cells of the pleura [1,8,9]. The disease has no symptoms in the early stages.…”