Mesoporous silica nanotechnology: promising advances in augmenting cancer theranostics

Dutta Gupta, Yashaswi; Mackeyev, Yuri; Krishnan, Sunil; Bhandary, Suman

doi:10.1186/s12645-024-00250-w

Cited by 7 publications

(1 citation statement)

References 239 publications

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“…With the expanding knowledge of cancer’s genetic and molecular foundations, nanotechnology can be harnessed to develop therapies tailored to individual patients. By customizing nanocarriers to match the distinct genetic makeup of a patient’s tumor, drug delivery and treatment efficacy can be optimized [ 218 , 222 ].…”

Section: Conclusion and Future Perspectivementioning

confidence: 99%

Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review

Arafat,

Sakkal,

Beiram

et al. 2024

Pharmaceuticals

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Cancer continues to pose one of the most critical challenges in global healthcare. Despite the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting and eliminating cancer cells while minimizing damage to healthy ones, thereby reducing treatment side effects. The revolutionary approach of utilizing nanomaterials for delivering cancer therapeutic agents has significantly enhanced the efficacy and safety of chemotherapeutic drugs. This crucial shift is attributed to the unique properties of nanomaterials, enabling nanocarriers to transport therapeutic agents to tumor sites in both passive and active modes, while minimizing drug elimination from delivery systems. Furthermore, these nanocarriers can be designed to respond to internal or external stimuli, thus facilitating controlled drug release. However, the production of nanomedications for cancer therapy encounters various challenges that can impede progress in this field. This review aims to provide a comprehensive overview of the current state of nanomedication in cancer treatment. It explores a variety of nanomaterials, focusing on their unique properties that are crucial for overcoming the limitations of conventional chemotherapy. Additionally, the review delves into the properties and functionalities of nanocarriers, highlighting their significant impact on the evolution of nanomedicine. It also critically assesses recent advancements in drug delivery systems, covering a range of innovative delivery methodologies. Finally, the review succinctly addresses the challenges encountered in developing nanomedications, offering insightful perspectives to guide future research in this field.

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Section: Conclusion and Future Perspectivementioning

confidence: 99%

Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review

Arafat,

Sakkal,

Beiram

et al. 2024

Pharmaceuticals

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A Review of Recent Advancements and Perspectives of Nanotechnology in the Application of Biomedical Imaging and Instrumentation

Walke,

Mandake,

Naniwadekar

2024

ChemistrySelect

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The development of imaging, diagnosis, prognosis and early detection of diseases has been greatly impacted by nanotechnology by enhancing already existing clinically applicable technologies. With the help of their capacity to alter nanoparticles for molecular‐level specificity, tissue‐specific diagnosis is made possible gratitude to the unique biophysical features of the nanoparticles that enable contrast augmentation will boost biomedical imaging. The unique prospect of multiplexing is possible by the fact that minute changes in the nanoparticles’ size or composition can have significant effects on their optical, magnetic, or electrical capabilities. This article examines nanotechnology's function in biomedical imaging. In this article, the fundamentals and applications of biomedical imaging, pharmaceutical application of microbial surfactants, intelligent drug delivery systems, and green metallic nanoparticle manufacturing are all examined. The biomedical applications comprising organic (carbon nanotubes, metal oxide and liposomes) and inorganic (metal oxide, metal) nanoparticles, and materials with nanopatterns in diagnostics, biosensing, and bioimaging devices, along with drug delivery systems, are the main topics of discussion. studies conducted in vitro and in vivo have demonstrated that different nanoparticles can be utilized to detect seizures early and precisely along with to treat them successfully. To decrease the possible toxicity and enable improved target specificity, respectively, more development in the synthesis and functionalization of adaptable nanotechnologies is required.

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Towards the preparation of smart drug delivery platforms for colorectal cancer therapy: Biocompatible and targeted mesoporous silica nanoparticles with the deferiprone-copper complex gatekeeper

Iranpour,

Abnous,

Taghdisi

et al. 2024

Journal of Drug Delivery Science and Technology

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Mesoporous silica nanotechnology: promising advances in augmenting cancer theranostics

Cited by 7 publications

References 239 publications

Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review

Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review

A Review of Recent Advancements and Perspectives of Nanotechnology in the Application of Biomedical Imaging and Instrumentation

Towards the preparation of smart drug delivery platforms for colorectal cancer therapy: Biocompatible and targeted mesoporous silica nanoparticles with the deferiprone-copper complex gatekeeper

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