Mesoporous silica nanoparticles combining two-photon excited fluorescence and magnetic properties

Chelebaeva, Elena; Raehm, Laurence; Durand, Jean‐Olivier; Guari, Yannick; Larionova, Joulia; Guérin, Christian; Trifonov, A. A.; Willinger, Marc Georg; Kalaivani, T.; Lascialfari, A.; Mongin, Olivier; Mir, Y.; Blanchard‐Desce, Mireille

doi:10.1039/b922052f

Cited by 33 publications

(16 citation statements)

References 77 publications

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“…The homogeneous dispersion of the superparamagnetic nanoparticles results in a reduction of the correlation time (t D ) and therefore the hyperfine interaction is more efficient in relaxing the nuclei. This effect may explain the increase in r 2 values for the ferrofluids of the surface coated samples with respect to the bare USM nanoparticles [14,[26][27][28].…”

Section: Resultsmentioning

confidence: 91%

Design of water-based ferrofluids as contrast agents for magnetic resonance imaging

Casula

Corrias

Arosio

et al. 2011

Journal of Colloid and Interface Science

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Section: Resultsmentioning

confidence: 91%

Design of water-based ferrofluids as contrast agents for magnetic resonance imaging

Casula

Corrias

Arosio

et al. 2011

Journal of Colloid and Interface Science

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“…The development of magnetic silica nanocomposites with multiple functionalities has become a very active field 27–29, 116–125. Preferably, the functionalities should combine the advantages of MRI, fluorescence, a surface functional group for targeting, and the ability to deliver drugs locally 126–131.…”

Section: Magnetic Mesoporous Silica Nanocompositesmentioning

confidence: 99%

“…By using a so‐called ‘surface‐protected etching’ process, multifunctional particles with a superparamagnetic Fe 3 O 4 core, a gold nanoshell, and a mesoporous silica outer layer were synthesized by Yin and collaborators 116–118. Multifunctional magnetic NPs combining both two‐photon excited fluorescence and MRI properties were developed using covalent anchoring of cyano‐bridged coordination polymer Fe 2+ /[Fe(CN) 6 ] 3 to the surface of two‐photon dye‐doped mesoporous silica NPs 119. A highly fluorescent, photostable, and magnetic core/shell nanoparticle in the submicrometer size range has been synthesized from a modified Stöber method combined with the layer‐by‐layer assembly technique by Salgueiriño‐Maceira et al128 In their further work, they synthesized bifunctional magnetic and optically tunable nanoparticles with a magnetic iron oxide core surrounded by a thick silica shell and further covered with an outer shell of gold 129.…”

Section: Magnetic Mesoporous Silica Nanocompositesmentioning

confidence: 99%

Magnetic Nanocomposites with Mesoporous Structures: Synthesis and Applications

Liu

Qiao

et al. 2011

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Magnetic nanocomposites with well-defined mesoporous structures, shapes, and tailored properties are of immense scientific and technological interest. This review article is devoted to the progress in the synthesis and applications of magnetic mesoporous materials. The first part briefly reviews various general methods developed for producing magnetic nanoparticles (NPs). The second presents and categorizes the synthesis of magnetic nanocomposites with mesoporous structures. These nanocomposites are broadly categorized into four types: monodisperse magnetic nanocrystals embedded in mesoporous nanospheres, microspheres encapsulating magnetic cores into perpendicularly aligned mesoporous shells, ordered mesoporous materials loaded with magnetic NPs inside the porous channels or cages, and rattle-type magnetic nanocomposites. The third section reviews the potential applications of the magnetic nanocomposites with mesoporous structures in the areas of heath care, catalysis, and environmental separation. The final section offers a summary and future perspectives on the state-of-the art in this area.

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“…The same group also successfully developed a new approach to synthesize multifunctional NPs by using covalent attachment of cyano-bridged coordination polymer Ni 2+ /[Fe(CN) 6 ] 3− to the surface of two-photon dye-doped MSNPs. These hybrid NPs combine effective two-photon excited fluorescence, porosity, high MRI efficiency and superparamagnetic properties [105]. …”

Section: Photodynamic Therapy and Imaging For Cancermentioning

confidence: 99%

Development and applications of photo-triggered theranostic agents

Rai

Mallidi

Zheng

et al. 2010

Advanced Drug Delivery Reviews

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329

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Theranostics, the fusion of therapy and diagnostics for optimizing efficacy and safety of therapeutic regimes, is a growing field that is paving the way towards the goal of personalized medicine for the benefit of patients. The use of light as a remote-activation mechanism for drug delivery has received increased attention due to its advantages in highly specific spatial and temporal control of compound release. Photo-triggered theranostic constructs could facilitate an entirely new category of clinical solutions which permit early recognition of the disease by enhancing contrast in various imaging modalities followed by the tailored guidance of therapy. Finally, such theranostic agents could aid imaging modalities in monitoring response to therapy. This article reviews recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents. Specifically, we discuss recent developments in the use of theranostic agents for photodynamic-, photothermal-or photo-triggered chemo-therapy for several diseases.

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Mesoporous silica nanoparticles combining two-photon excited fluorescence and magnetic properties

Cited by 33 publications

References 77 publications

Design of water-based ferrofluids as contrast agents for magnetic resonance imaging

Design of water-based ferrofluids as contrast agents for magnetic resonance imaging

Magnetic Nanocomposites with Mesoporous Structures: Synthesis and Applications

Development and applications of photo-triggered theranostic agents

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