Mesoporous MnCo2O4 with efficient peroxidase mimetic activity for detection of H2O2

Vetr, Fahime; Moradi‐Shoeili, Zeinab; Özkâr, Saim

doi:10.1016/j.inoche.2018.10.024

Cited by 14 publications

(7 citation statements)

References 59 publications

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“…Moreover, the peroxidase‐like activity of CuCo 2 S 4 NPs was also investigated by colorimetric method using o‐phenylenediamine (OPD) as substrate . Typical UV/Vis absorption of oxidized OPD (oxOPD) at 417 nm appeared when incubated with CuCo 2 S 4 NPs in the presence of H 2 O 2 , confirming their peroxidase‐like activity (Figure S7a).…”

Section: Resultsmentioning

confidence: 69%

“…The enhanced peroxidase‐like activity of CuCo 2 S 4 NP was further investigated by steady‐state kinetic experiments (Figure S8). The enzymatic kinetic parameters including Michaelis‐Menten constant ( K m ) and maximum initial velocity ( V max ) were obtained (Table S2) . Compared with CuS and CoS NPs, CuCo 2 S 4 NPs confirmed the higher activity, with much larger V max values.…”

Section: Resultsmentioning

confidence: 99%

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Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Guo

Ding

et al. 2020

ChemBioChem

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Peroxidase‐mimicking nanozymes that can generate toxic hydroxyl radicals (.OH) hold great promise as antibacterial alternatives. However, most of them display optimal performance under strongly acidic conditions (pH 3–4), and are thus not feasible for many medical uses, including burn infections with a wound pH close to neutral. Herein, we report a copper‐based nanozyme (CuCo2S4) that exhibits intrinsic peroxidase‐like activity and can convert H2O2 into .OH at neutral pH. In particular, bimetallic CuCo2S4 nanoparticles (NPs) exhibited enhanced peroxidase‐like activity and antibacterial capacity, superior to that of the corresponding monometallic CuS and CoS NPs. The CuCo2S4 nanozymes possessed excellent ability to kill various bacteria, including methicillin‐resistant Staphylococcus aureus (MRSA). Furthermore, this CuCo2S4 nanozymes could effectively disrupt MRSA biofilms in vitro and accelerate MRSA‐infected burn healing in vivo. This work provides a new peroxidase mimic to combat bacteria in neutral pH milieu and this CuCo2S4 nanozyme could be a promising antibacterial agent for the treatment of burn infections.

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Section: Resultsmentioning

confidence: 69%

Section: Resultsmentioning

confidence: 99%

Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Guo

Ding

et al. 2020

ChemBioChem

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“…Supporting the metal complexes onto nanomaterials such as metal oxides is a widely strategy to overcome these limitations. Magnetite nanoparticles, in particular spinel ferrites‐ such as MnFe 2 O 4 nanoparticle are largely employed for this purpose due to their high saturation magnetization, high mechanical hardness and chemical stability …”

Section: Introductionmentioning

confidence: 98%

Manganese Ferrite Nanoparticles Modified by Mo(VI) Complex: Highly Efficient Catalyst for Sulfides and Olefins Oxidation Under Solvent‐less Condition

et al. 2019

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In this research work, we report a new Mo(VI) Schiff base complex based on 1,3‐bis(4‐bromo‐2‐carboxyaldehyde phenoxy)propane, which was immobilized covalently on MnFe2O4 magnetic nanoparticles. The efficiency of the novel catalyst was investigated for the oxidation of olefins and organic sulfides. Under optimized conditions, the nanoparticle catalyst allowed selective epoxidation of cis‐cyclooctene, cyclohexene, and cis‐cyclodecane with 99% conversion in 10 min under solvent‐free condition with tert‐butyl hydroperoxide as oxidant. The catalyst also showed excellent ability for the oxidation of thioanisole, dimethyl sulfide and benzyl phenyl sulfide with a 99% conversion in 5 min and solvent‐less condition with H2O2 (30%) as oxidant. The recyclability of catalyst was also investigated in the oxidation of cyclooctene and methyl phenyl sulfide at least for 5 times.

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“…Cholesterol can be decomposed under the catalysis of cholesterol oxidase (ChOx) to produce H 2 O 2 , as shown in eq 1. Therefore, cholesterol levels can be determined by evaluating the content of H 2 O 2 . With the progress of science and technology, H 2 O 2 detection methods have been constantly upgraded, from fluorescence and colorimetric methods to the electrochemical method. − However, among them, the colorimetric method has the advantages of low cost, strong practicability, high efficiency, and simplicity in practical applications. Horseradish peroxidase (HRP), a kind of natural peroxidase, is known as a precise biocatalyst for H 2 O 2 colorimetric sensors.…”

Section: Introductionmentioning

confidence: 99%

Porphyrin-Modified NiS₂ Nanoparticles Anchored on Graphene for the Specific Determination of Cholesterol

Zhu

Xue

et al. 2021

ACS Appl. Nano Mater.

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Exploring peroxidase-like nanozymes with high catalytic activity is an urgent task to construct a fast, convenient, and selective colorimetric sensing platform. In this work, a nanozyme, 5,10,15,20-tetrakis(4-carboxyl phenyl)porphyrin-functionalized NiS 2 nanoparticles, anchored on the surface of graphene (Por-NiS 2 /GO) was designed. Compared with NiS 2 nanoparticles anchored on the surface of graphene (NiS 2 /GO), Por-NiS 2 /GO had a higher peroxidase-like activity due to the introduction of porphyrin. The size of NiS 2 nanoparticles was about 110−250 nm. The peroxidase-like behaviors of Por-NiS 2 /GO were evaluated using the chromogenic substrate 3,3′,5,5′-tetramethylbenzidine (TMB) with a fast-blue color change in less than 1 min. Electron spin resonance (ESR) data revealed that the excellent performance of Por-NiS 2 / GO was due to the active oxygen species produced, including hydroxyl radical ( • OH) and superoxide radical ( • O 2 − ), during the catalytic reaction, owing to the synergetic effect among different components including porphyrin, NiS 2 , and GO. Thus, based on the enhanced peroxidase-like activity of Por-NiS 2 /GO, a fast, sensitive, and selective colorimetric sensing platform of H 2 O 2 has been constructed, and furthermore, a sensing platform for cholesterol was also developed coupled with cholesterol oxidase (ChOx). The colorimetric sensing platform was validated by detecting cholesterol in serum samples.

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Mesoporous MnCo2O4 with efficient peroxidase mimetic activity for detection of H2O2

Cited by 14 publications

References 59 publications

Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Manganese Ferrite Nanoparticles Modified by Mo(VI) Complex: Highly Efficient Catalyst for Sulfides and Olefins Oxidation Under Solvent‐less Condition

Porphyrin-Modified NiS₂ Nanoparticles Anchored on Graphene for the Specific Determination of Cholesterol

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Mesoporous MnCo2O4 with efficient peroxidase mimetic activity for detection of H2O2

Cited by 14 publications

References 59 publications

Bimetallic CuCo2S4 Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Bimetallic CuCo2S4 Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Manganese Ferrite Nanoparticles Modified by Mo(VI) Complex: Highly Efficient Catalyst for Sulfides and Olefins Oxidation Under Solvent‐less Condition

Porphyrin-Modified NiS2 Nanoparticles Anchored on Graphene for the Specific Determination of Cholesterol

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Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Bimetallic CuCo₂S₄ Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Porphyrin-Modified NiS₂ Nanoparticles Anchored on Graphene for the Specific Determination of Cholesterol