We report a measurement of the differential cross section of π 0 pair production in single-tag two-photon collisions, γ * γ → π 0 π 0 , in e + e − scattering. The cross section is measured for Q 2 3 up to 30 GeV 2 , where Q 2 is the negative of the invariant mass squared of the tagged photon, in the kinematic range 0.5 GeV < W < 2.1 GeV and | cos θ * | < 1.0 for the total energy and pion scattering angle, respectively, in the γ * γ center-of-mass system. The results are based on a data sample of 759 fb −1 collected with the Belle detector at the KEKB asymmetric-energy e + e − collider. The transition form factor of the f0(980) and that of the f2(1270) with the helicity-0, -1, and -2 components separately are measured for the first time and are compared with theoretical calculations.