Mesh fixation with sutures versus fibrin sealant in hernioplasty with reabsorbable prosthesis (polyglycolic acid and trimethylene carbonate). Experimental study in animals

Suárez-Grau, Juan Manuel; Morales‐Conde, Salvador; Martín-Cartes, Juan Antonio; Cháves, C. Rubio; Jiménez, Mario de Jesús Pérez; Ramírez, Francisco Palma; Docobo-Durantez, Fernando; Méndez, S. Morales

doi:10.1016/s2173-5077(09)70094-8

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…Increasing angiogenesis and fibroblast growth, enriched with growth factors, which totally replace the mechanical fastening [5].…”

Section: New Activated Biological Adhesivesmentioning

confidence: 99%

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Research into Materials Used in Abdominal Wall Repair

Manuel¹

2015

Pharmaceut Reg Affairs

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The future of research in the treatment of hernia is directed mainly in two ways. The first is in genetic research, focusing on the goal of preventing the occurrence of hernia. The second (and more realistic), addresses the introduction of a new generation of biomaterials and surgical techniques that minimize aggression hernia repair, reduce surgical time and facilitate post-operative recovery of these patients. In this second line of action appear the most important advances in the field of minimally invasive techniques and materials used to repair the hernia pathology.The development of materials currently employed in hernia surgery has focused almost entirely on improvements on the screens, coatings and methods of fixation. The point has been reached of trying to unite these concepts, creating new self-adhesive mesh, coated meshes of various substances that incorporate improvements in both fields of research.

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“…Increasing angiogenesis and fibroblast growth, enriched with growth factors, which totally replace the mechanical fastening [5].…”

Section: New Activated Biological Adhesivesmentioning

confidence: 99%

“…-Growth factors (GF) may apply to fibroproliferative and angiogenic stimulators such as bTGF, bFGF and PDGF (very derivatives present in the fibrin glue, which increases angiogenesis, improving the integration of the mesh fixed with biological glues) [5,[9][10][11][12][13][14][15].…”

Section: Activating Regeneration: Stem Cellsmentioning

confidence: 99%

Research into Materials Used in Abdominal Wall Repair

Manuel¹

2015

Pharmaceut Reg Affairs

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Correction to: Fixation of polyvinylidene fluoride (PVDF) mesh with cyanoacrylate-derived glues in a rat experimental model: histopathologic immunohistochemical and morphometric study

Poli

Parisi

Millanta

et al. 2020

Hernia

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The Use of Surgical Adhesive and Suture Fixing Meshes to the Abdominal Wall: An Experimental Study in Rats

Utrabo

Busato

Netto

et al. 2022

ABCD, arq. bras. cir. dig.

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- BACKGROUND: Proper fixation of the surgical mesh determines the success of a herniorrhaphy. Understanding the inflammatory response and the mechanical properties of the mesh helps to define whether a fixation method is superior. AIM: This study aimed to evaluate the healing of defects in the abdominal wall of rats, comparing the repair of macroporous polypropylene meshes fixed with surgical glue and polypropylene thread. METHODS: In 20 Wistar rats, a defect was produced in the abdominal wall, with the integrity of the parietal peritoneum. For correction, the meshes were fixed with surgical glue (2-octyl cyanoacrylate) (subgroup C1), or polypropylene suture (subgroup C2). The two subgroups of 10 animals were euthanized on the 90th postoperative day, and the fragments of the abdominal wall were submitted to macroscopic, histological, and tensiometric analysis. RESULTS: Macroscopic analysis did not show any abnormalities. Tensiometry on the 90th postoperative day in subgroup C1 showed mean rupture tension of 28.47N and in subgroup C2 32.06N (p=0.773). The inflammatory process score revealed that both groups are in the subacute phase (p=0.380). CONCLUSION: The fixation of a polypropylene macroporous mesh to repair an abdominal wall defect can be performed with surgical glue (2-octyl cyanoacrylate) or polypropylene suture, both methods being equally effective.

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Mesh fixation with sutures versus fibrin sealant in hernioplasty with reabsorbable prosthesis (polyglycolic acid and trimethylene carbonate). Experimental study in animals

Cited by 3 publications

References 18 publications

Research into Materials Used in Abdominal Wall Repair

Research into Materials Used in Abdominal Wall Repair

Correction to: Fixation of polyvinylidene fluoride (PVDF) mesh with cyanoacrylate-derived glues in a rat experimental model: histopathologic immunohistochemical and morphometric study

The Use of Surgical Adhesive and Suture Fixing Meshes to the Abdominal Wall: An Experimental Study in Rats

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