Mesenteric panniculitis with pedal edema in a 33-year-old Pakistani man: a case report and literature review

Zafar, Abdul Mueed; Rauf, Muhammad Abdur; Chawla, Tabish; Khanda, Gule

doi:10.1186/1752-1947-2-365

Cited by 9 publications

(21 citation statements)

References 11 publications

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“…Most studies have indicated that the disease is more common in men with a male/female ratio of 2-3:1, more frequent between the 6 th and 7 th decades of life and several reports have indicated it to be more common in Caucasian men (1,3,5,8,11,19). Pediatric cases are exceptional, probably because children have less mesenteric fat when compared to adults.…”

Section: Methodsmentioning

confidence: 98%

“…The vast majority of cases of Sclerosing Mesenteritis (SM) (comprising the large majority subgroup of MP) are considered as idiopathic and benign (8). The pathogenic mechanism of MP could be a nonspecific response to a wide variety of stimuli (1).…”

Section: Methodsmentioning

confidence: 99%

“…creatitis, bile or urine leakage, hypersensitivity reactions, and even bacterial infection (2,4,8,(13)(14)(15)19). Other factors, such as gallstones, coronary disease, cirrhosis, abdominal aortic aneurysm, peptic ulcer, or chylous ascitis, have also been linked to this disease (20).…”

Section: # #mentioning

confidence: 99%

“…It was first described by Jura (6) in 1924 as "Retractile Mesenteritis" and further labeled as "Mesenteric Panniculitis" by Odgen (7) later in the 1960s. Only few large series have been reported and the literature comprises mainly case reports and studies of small series (8)(9)(10). Currently, the pathology has several names: sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric panniculitis, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery (1,3,4,(11)(12)(13)(14).…”

Section: Generalitiesmentioning

confidence: 99%

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Mesenteric panniculitis part 1: mdct - pictorial review

Coulier

2011

Journal of the Belgian Society of Radiology

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Mesenteric panniculitis is an uncommon benign inflammatory condition of unknown etiology that involves the adipose tissue of the mesentery and for which an extremely varied terminology has been used, causing considerable confusion. It can be evaluated as a single disease with two pathological subgroups: Mesenteric Panniculitis (MP), representing the very large major subgroup where inflammation and fat necrosis predominate and Retractile Mesenteritis (RM), much rarely found, where fibrosis and retraction predominate. In histo-pathological terms the preferred terminology is sclerosing mesenteritis. We hereby extensively illustrate the characteristic MDCT findings of MP through pictures selected among a collection of cases constituted over a 5-year period. All patients were scanned with 64-row MDCT equipment. We also review the literature and discuss the differential diagnosis. The radiological diagnosis of MP was based on classical CT signs described in the literature and comprising: the presence of a well-defined "mass effect" on neighbouring structures (sign 1) constituted by mesenteric fat tissue of inhomogeneous higher attenuation than adjacent retroperitoneal or mesocolonic fat (sign 2) and containing small soft tissue nodes (sign 3). It may typically be surrounded by a hypoattenuated fatty "halo sign" (sign 4) and an hyperattenuating pseudocapsule may also surround the all entity (sign 5). The last two signs are considered inconstant but very specific. The absence of histological verification constitutes the weakness of our study. The differential diagnosis of MP is extensive and includes all disorders that can affect the mesentery. The most common ones are lymphoma, well-differentiated liposarcoma, peritoneal carcinomatosis, carcinoid tumor, retroperitoneal fibrosis, lipoma, mesenteric desmoid tumor, mesenteric inflammatory pseudotumor, mesenteric fibromatosis and mesenteric edema. PET/CT is proved useful to correctly exclude mesenteric tumoral involvement in patients presenting with typical MP. The course of MP is favorable in most cases and progression of MP to retractile mesenteritis not only appears very being rare but finally remains doubtful.

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Section: Methodsmentioning

confidence: 98%

Section: Methodsmentioning

confidence: 99%

Section: # #mentioning

confidence: 99%

Section: Generalitiesmentioning

confidence: 99%

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Mesenteric panniculitis part 1: mdct - pictorial review

Coulier

2011

Journal of the Belgian Society of Radiology

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“…A wide variety of clinical manifestations of MP have been described which are very inconstant and nonspecific (1, 3) but as many as half of the cases reported MP has been an incidental finding in asymptomatically presenting patients (3,16). It's also our opinion that this proportion of asymptomatic presentations is extremely much higher.…”

Section: Discussionmentioning

confidence: 99%