Mesenteric Panniculitis Associated With Vibrio cholerae Infection

Roginsky, Grigory; Mazulis, Andrew; Ecanow, Jacob S.; Ehrenpreis, Eli D.

doi:10.14309/crj.2015.95

Cited by 14 publications

(6 citation statements)

References 18 publications

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“…Several atypical microorganisms such as Cryptococcus neoformans and Mycobacterium genavense have been reported in HIV patients in relation to MP [14,15]. On the other hand, M. tuberculosis and Vibrio cholera are suspected to be the infectious agents that cause MP in immunocompetent patients [16,17]. In addition, various acute abdominal inflammatory disorders in which enteric bacteria was involved in the etiopathogenesis, such as diverticulitis and acute appendicitis, have been reported in relation to MP [18].…”

Section: Discussionmentioning

confidence: 99%

An Overlooked Potentially Treatable Disorder: Idiopathic Mesenteric Panniculitis

Şahin¹,

Artaş

Eroğlu

et al. 2017

Med Princ Pract

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Objective: The aim of this study was to determine the prevalence of mesenteric panniculitis (MP) and to describe its clinical characteristics, therapy, and outcome. Subjects and Methods: This retrospective study was carried out among patients with MP based on computed tomography (CT) scans from January 2012 to December 2015. The CT images were reanalyzed by study radiologists to confirm the previous MP diagnosis. Patients were divided into 2 groups, i.e., idiopathicandsecondary, based on the presence or absence of associated predisposing factors such as trauma, malignancy, autoimmune disorders, ischemia, or previous abdominal surgery. The clinical characteristics of the 2 groups, as well as treatments, were assessed. Results: Among the 19,869 CT scans, 36 patients (0.18%) with MP were identified (i.e., 19 [53%] females and 17 [47%] males). The median age was 54 years (range 26 - 76). Twenty-four patients (67%) were categorized into the idiopathic group. Malignancy was the predisposing factor in 8 (22%) of those patients. Furthermore, abdominal pain was the cardinal symptom observed in 22 patients (92%) in the idiopathic group. In the idiopathic group, 15 patients (63%) were treated with antibiotics and 16 (67%) were treated with nonsteroidal anti-inflammatory drugs (NSAID). One unresponsive patient was treated with colchicine. Symptomatic relief was achieved in all of the treated patients. Conclusion: In thisstudy, a symptomatic idiopathic subgroup of patients with MP did not have any associated disorder. The response to treatment with antibiotics and NSAID was effective in most of the patients. Based on these findings, anti-inflammatory treatments beyond NSAID and surgery should be reserved for patients who are unresponsive to antibiotics and NSAID.

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Section: Discussionmentioning

confidence: 99%

An Overlooked Potentially Treatable Disorder: Idiopathic Mesenteric Panniculitis

Şahin¹,

Artaş

Eroğlu

et al. 2017

Med Princ Pract

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“…A variety of conditions are associated with MP including abdominal trauma[4], lymphoma and other neoplasms[5,6] and autoimmune diseases[7-9]. Infectious associations with MP include mycobacterial[10] and cryptococcal[11] infections and cholera[12]. In some patients, especially those having an acute presentation of the disease, a viral mesenteritis is likely.…”

Section: Introductionmentioning

confidence: 99%

Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms

Ehrenpreis

Roginsky

Gore

2016

WJG

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AIMTo clarify the association of malignancy with mesenteric panniculitis-like changes on computed tomography (CT).METHODSAll abdominal CT scans performed at NorthShore University HealthSystem showing mesenteric panniculitis from January 2005 to August 2010 were identified in the Radnet (RadNet Corporation, Los Angeles, CA) database. Patients with a new or known diagnosis of a malignancy were included for this analysis. Longitudinal clinical histories were obtained from electronic medical records.RESULTSIn total, 147794 abdominal CT scans were performed during the study period. Three hundred and fifty-nine patients had mesenteric panniculitis (MP)-like abnormalities on their abdominal CT. Of these patients, 81 patients (22.6%) had a known history of cancer at the time of their CT scan. Nineteen (5.3%) had a new diagnosis of cancer in concurrence with their CT, but the majority of these (14/19, 74%) were undergoing CT as part of a malignancy evaluation. Lymphomas were the most common cancers associated with MP-like findings on CT (36 cases, 36%), with follicular lymphoma being the most frequent subtype (17/36). A variety of solid tumors, most commonly prostate (7) and renal cell cancers (6) also were seen. CT follow up was obtained in 56 patients. Findings in the mesentery were unchanged in 45 (80%), worsened in 6 (11%), and improved in 5 patients (9%). Positron emission tomography (PET) scans performed in 44 patients only showed a positive uptake in the mesenteric mass in 2 patients (5%).CONCLUSIONA new diagnosis of cancer is uncommon in patients with CT findings suggestive of MP. MP-like mesenteric abnormalities on CT generally remain stable in patients with associated malignancies. PET scanning is not recommended in the evaluation of patients with mesenteric panniculitis-like findings on CT.

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“…The misty mesentery sign can occur in various conditions, like trauma, abdominal cancer, and infections (3). Regarding the latter, Roginsky et al described it in one patient with Vibrio Cholerae but it was not previously reported in COVID-19 patients (4). The fact that in our cohort the misty mesentery sign was associated with higher levels of CRP lets us assume that the hyperinflammation due to COVID-19 may be the cause (5).…”

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confidence: 49%