Mesenteric Lymph Node Cavitation in Celiac Disease

Reddy, D. Ramachandra; Salomon, Caryl G.; Demos, Terrence C; Cosar, Ediz F.

doi:10.2214/ajr.178.1.1780247

Cited by 30 publications

(22 citation statements)

References 4 publications

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“…The characteristic CT feature is that of enlarged mesenteric nodes containing fat-fluid levels and allows an imaging-specific diagnosis (Fig 8). The specific cause of cavitation remains uncertain, but the finding has been associated with a poor outcome (9). Additional CT findings of celiac disease may be apparent, such as nonobstructive dilatation of the proximal small bowel.…”

Section: Pickhardt and Bhalla 721mentioning

confidence: 99%

Unusual Nonneoplastic Peritoneal and Subperitoneal Conditions: CT Findings

Pickhardt¹,

Bhalla²

2005

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Peritoneal disease can manifest at computed tomography (CT) as fluid accumulation within the peritoneal cavity (ascites) or soft-tissue infiltration of the various peritoneal ligaments and mesenteries. Beyond the commonly encountered cases of typical ascites and peritonitis, there is a wide spectrum of uncommon nonneoplastic conditions that may involve the peritoneal and subperitoneal spaces. For example, systemic or organ-based diseases that occasionally involve the peritoneum include eosinophilic gastroenteritis, amyloidosis, extramedullary hematopoiesis, Erdheim-Chester disease, sarcoidosis, and mesenteric cavitary lymph node syndrome. Tumorlike conditions that may affect the peritoneum include aggressive fibromatosis (desmoid), inflammatory pseudotumor, retractile mesenteritis, and Castleman disease. Atypical peritoneal infections include tuberculosis, actinomycosis, echinococcosis, Whipple disease, and mesenteric adenitis. Conditions involving the subperitoneal fat include epiploic appendagitis, mesenteric panniculitis, and segmental omental infarction, all of which have characteristic CT findings. CT is an excellent imaging modality for detection and characterization of peritoneal involvement from these unusual diseases.

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Section: Pickhardt and Bhalla 721mentioning

confidence: 99%

Unusual Nonneoplastic Peritoneal and Subperitoneal Conditions: CT Findings

Pickhardt¹,

Bhalla²

2005

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112

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“…Occasionally, the syndrome may be present at the time of initial presentation and diagnosis of underlying celiac disease. The CT and sonographic features of cavitating mesenteric lymph node syndrome have previously been reported [1][2][3][4][5]. To our knowledge, the MRI findings of this syndrome have not yet been described.…”

mentioning

confidence: 77%

“…On CT, these cystic mesenteric masses have central low attenuation with thin enhancing rims. The central material may be of fluid or fat attenuation [1,4,5]. Fatfluid levels within the masses may be apparent on CT [4].…”

Section: Discussionmentioning

confidence: 99%

“…The central material may be of fluid or fat attenuation [1,4,5]. Fatfluid levels within the masses may be apparent on CT [4]. Sonographically, the mesenteric masses appear as anechoic cysts [2,3,5].…”

Section: Discussionmentioning

confidence: 99%

“…Thus, in some patients, celiac disease may not be suspected, and the patient may present at a later stage. The imaging findings of cystic mesenteric nodes, with or without fatfluid levels, may allow the radiologist to suggest cavitating mesenteric lymph node syndrome associated with previously undiagnosed celiac disease [4]. Expedient diagnosis is important to decrease the morbidity and mortality associated with untreated celiac disease and the associated increased risk of malignancy.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Diagnosis of Cavitating Mesenteric Lymph Node Syndrome in Celiac Disease Using MRI

Huppert

Farrell

Kawashima

et al. 2004

American Journal of Roentgenology

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Enteropathy‐associated intestinal T‐cell lymphoma in cavitating mesenteric lymph node syndrome: Fine‐needle aspiration contributes to the diagnosis

Schwock

Hyjek

Torlakovic

et al. 2014

Diagnostic Cytopathology

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Cavitating mesenteric lymph node syndrome (CMLNS) is an infrequently reported manifestation of unrecognized/longstanding celiac disease and may be associated with enteropathy-associated intestinal T-cell lymphoma and hyposplenism. Unrecognized malignancy and life-threatening infections can pose a significant risk to patients in cases of delayed diagnosis. Fine-needle aspiration of the mesenteric lesions may contribute significantly to the correct diagnosis and can expedite patient management. We report on the cytologic characteristics of enteropathy-associated intestinal T-cell lymphoma first detected in a cyst fluid specimen obtained from a patient with cavitating mesenteric lesions. Image-guided fine-needle aspiration resulted in chylous fluid that contained a lymphoid cell population with neoplastic morphology and abnormal immunophenotype. Further work-up led to the diagnosis of enteropathy-associated intestinal T-cell lymphoma with bone marrow involvement. Cytologic assessment of the cyst fluid is an important part of the diagnostic cascade in patients with CMLNS to exclude clinically occult lymphoma.

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Mesenteric Lymph Node Cavitation in Celiac Disease

Cited by 30 publications

References 4 publications

Unusual Nonneoplastic Peritoneal and Subperitoneal Conditions: CT Findings

Unusual Nonneoplastic Peritoneal and Subperitoneal Conditions: CT Findings

Diagnosis of Cavitating Mesenteric Lymph Node Syndrome in Celiac Disease Using MRI

Enteropathy‐associated intestinal T‐cell lymphoma in cavitating mesenteric lymph node syndrome: Fine‐needle aspiration contributes to the diagnosis

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