Mesenteric desmoid tumor developing on the site of an excised gastrointestinal stromal tumor

Khan, Mohammad; Bozas, George; Jp, Cooke; Wedgwood, K. R.; Maraveyas, Anthony

doi:10.4081/rt.2010.e33

Cited by 9 publications

(13 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…IAF has been observed in the sites of previous abdominal surgery for tumors [23,24]. Its diagnosis often is difficult to establish preoperatively, and it is usually misdiagnosed as recurrence at first clinical impression [2,22,23,27]. Surgical excision of the lesion is a difficult decision owing to the suspicion of metastasis mainly due to the following reasons.…”

Section: Discussionmentioning

confidence: 99%

“…In these cases, IAF was first misdiagnosed as GIST recurrence [2,3]. Very recently, a non-random association between GIST and IAF was described.…”

Section: Discussionmentioning

confidence: 99%

“…However, the two cases reported had been treated with imatinib at a dose of 400 mg for liver metastatic GIST. One achieved four years of long-term stable control [3] and the other achieved 11 months of disease control [2], but both developed IAF in primary GIST bed. The second patient was not benefit from imatinib therapy at this dosage.…”

Section: Discussionmentioning

confidence: 99%

“…With the accumulation of knowledges on GIST and long-time follow-up information, GIST patients are found to simultaneously or metachronously have other types of tumors [2-7], some of which are easier to be differentiated from GIST [4,6], while others might be confused with recurrent GIST from the clinical point of view [2,3]. …”

Section: Introductionmentioning

confidence: 99%

“…IAF developed after abdominal surgery and individual with both GIST and IAF were reported recently [2,3] and non-random association between GIST and IAF was established very recently based on data from 10 medical centers [12]. …”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Subsequent intra-abdominal fibromatosis mimicking recurrent gastrointestinal stromal tumor

Jiang

Hou

et al. 2013

Diagn Pathol

View full text Add to dashboard Cite

Intra-abdominal fibromatosis (IAF) commonly develops in patients who had abdominal surgery. In rare instances, it occurs subsequent to gastrointestinal stromal tumor (GIST). This special situation has clinical significance in imatinib era. About 1000 patients with GIST in our institution from 1993 to 2010 were re-evaluated based on their clinical and pathological data, the treatment strategies and the follow-up information. We identified 2 patients who developed IAF after GIST resection. Patient 1 was a 54 year-old male and had 5 cm × 4.5 cm × 3.5 cm jejunal GIST excised on February 22, 1994. Three years later, an abdominal mass with 7 cm × 6 cm × 3 cm was identified. He was diagnosed as recurrent GIST from clinical point of view. After excision, the second tumor was confirmed to be IAF. Patient 2 was a 45-year-old male and had 6 cm × 4 cm × 3 cm duodenal GIST excised on August 19, 2008. One year later, a 4 cm mass was found at the original surgical site. The patient refused to take imatinib until the tumor increased to 8 cm six months later. The tumor continued to increase after 6 months’ imatinib therapy, decision of surgical resection was made by multidisciplinary team. The second tumor was confirmed to be IAF with size of 17 cm × 13 cm × 11 cm. Although IAF subsequent to GIST is very rare, it is of clinical significance in imatinib era as an influencing factor for making clinical decision.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1076715989961803

show abstract