Mesenchymal Tumors of the Pancreas: CT Findings

Ferrozzi, F; Zuccoli, Giulio; Bova, Davide; Calculli, Lucia

doi:10.1097/00004728-200007000-00021

Cited by 88 publications

(54 citation statements)

References 19 publications

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“…Differential diagnosis of fat-containing pancreatic tumours with direct invasion of pancreatic tissue should be mentioned (i.e. malignant fibrous histiocytoma, leiomyosarcoma, desmoids tumour, cystic teratoma, fibrolipoma, liposarcoma and lipoblastoma) [10][11][12]. However, as in our case, fat-containing tumours originating from the pancreas may be ACC with fatty change.…”

Section: Discussionmentioning

confidence: 64%

Acinar cell carcinoma with fatty change arising from the pancreas

Chung

Park²,

Dw³

2011

BJR

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ABSTRACT. Acinar cell carcinoma of the pancreas is a rare malignant tumour developing from acinar cells, accounting for approximately 1% of pancreatic exocrine tumours. We experienced a case of an acinar cell carcinoma with fatty change. To the best of our knowledge, this is the first case report of an acinar cell carcinoma with fatty change in the clinical literature. Acinar cell carcinoma (ACC) of the pancreas is a malignant tumour developing from acinar cells. It is a rare tumour accounting for approximately 1% of pancreatic exocrine tumours. ACC with fatty change is extremely rare in the literature. This is a report on a 72-year-old female who was found to have ACC with fatty change. Case reportA 72-year-old female underwent a partial gastrectomy with Billroth I for early gastric cancer in September 2009. When a pancreatic mass was found during the 6-month follow-up CT, the patient was admitted for further investigation.Test results showed elevated levels of alpha-fetoprotein (AFP): 1945 IU ml 21 (normal range: 0-7 IU ml 21) and normal levels of cancer antigen 19-9: 8.5 U ml 21 (normal range: 0-37 U ml 21) and carcinoembryonic antigen (CEA): 2.31 ng ml 21 (normal range: 0-5 ng ml 21). An abdominal ultrasound showed a 2.5-cm hypoechoic mass in the neck of the pancreas. The mass was illdelimitated and heterogeneous. Contrast-enhanced CT showed a 2.5-cm mass in the neck of the pancreas with distal pancreatic duct dilatation and parenchymal atrophy. The mass was adjacent to the portal vein and showed less intense enhancement than the pancreas. No dilatation of the bile ducts, focal hepatic lesions or abdominal lymphadenopathies was found. The initial differential diagnoses were pancreatic cancer and metastasis.Positron emission tomography (PET) showed no significant increase in fluorodeoxyglucose (FDG) uptake. MRI showed a 2.5-cm hypovascular well-defined mass at the neck of the pancreas with distal pancreatic duct dilatation and parenchymal atrophy. This mass had low signal intensity at T 2 weighted imaging with fat suppression, and had a fat component at in-phase and outof-phase images (Figure 1). The portal vein was compressed and displaced by the mass, which remained permeable without invasion.A Whipple procedure was performed on the patient. The specimen revealed an ill-defined lobulating mass of 1.961.7 cm, which was confined to the pancreas. Histologically, the mass showed an acinar pattern of cells with nucleoli ( Figure 2). The tumour cells showed extensive and various degrees of clear cell change and microvesicular and macrovesicular fatty change. The tumour cells showed strong and diffuse immunoreactivity for AFP and were negative for CD56, chromogranin A and synaptophysin. Pathological diagnosis was ACC with fatty change.

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Section: Discussionmentioning

confidence: 64%

Acinar cell carcinoma with fatty change arising from the pancreas

Chung

Park²,

Dw³

2011

BJR

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“…1 The pancreas is an uncommon location for lipomas and pancreatic lipomas are usually detected as incidental findings on CT and MR studies. 2 These lipomas have characteristic imaging features which allow a correct diagnosis to be made without histopathological confirmation.…”

Section: Discussionmentioning

confidence: 99%

“…1 Various mesenchymal tumours have been reported in literature including lipoma, teratoma, schwannoma, neurofibroma, lymphoma and sarcoma. Pancreas is an uncommon location for a lipoma.…”

Section: Introductionmentioning

confidence: 99%

A rare tumour of pancreas in an incidentally discovered pancreatic lipoma

Kishan

Bhuvana

et al. 2015

Medical Journal Armed Forces India

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“…For preoperative diagnosis, computed tomography (CT), ultrasonography, magnetic resonance image (MRI), and angiography are useful for locating the tumor site, but can not be confirmed the definitive diagnosis. CT findings usually show well -defined, round masses with multiple, low -attenuation, and cystic necrotic areas 7) . On MRI, schwannomas are present as masses of low signal intensity on T1 -weighted images and of high signal intensity on T2 -weighted images 8) .…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Gallbladder: Report of a Case

Ohta

Hirata

Oneyama

et al. 2010

FJMS

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:We report a schwannoma of the gallbladder in a 58 -year -old man who was diagnosed as cholecystolithiasis. He presented with recurrent episodes of abdominal pain in the right upper quadrant. The abdominal computed tomography scan and ultrasonography revealed stones about 15 mm in diameter in the gallbladder. Under the diagnosis of cholecystolithiasis, laparoscopic cholecystectomy was performed. The resected specimen showed chronic cholecystitis and no suspicion of neoplasm. Pathological examination revealed that the tumor consist of spindle cells without atypical appearance at small area of fundus. Immunohistologically, tumor cells were positive for S -100 protein and negative for alpha -SMA and c -kit, the lesion was diagnosed as schwannoma.

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Mesenchymal Tumors of the Pancreas: CT Findings

Cited by 88 publications

References 19 publications

Acinar cell carcinoma with fatty change arising from the pancreas

Acinar cell carcinoma with fatty change arising from the pancreas

A rare tumour of pancreas in an incidentally discovered pancreatic lipoma

Schwannoma of the Gallbladder: Report of a Case

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