Mesenchymal Stem Cells and Their Derived Conditioned Media as Crucial Cell Candidates for Wound Healing: A Letter

Abstract

Mesenchymal stem cells (MSCs) are one of the most popular and important cells used in medical research and clinical studies in the past few decades. These cells can be characterized based on several parameters, including plastic attachment capacity, tri-lineage differentiation, and surface-specific marker expression. In addition, MSCs can be recognized by unique features, such as high proliferation and differentiation, immune-modulating capacity, lacked or low expression of immune responserelated molecules (such as major histocompatibility complex [MHC] class II), angiogenic, and regenerative mechanisms. Moreover, by using the paracrine process, MSCs