Mesenchymal Stem Cell–Laden In Situ–Forming Hydrogel for Preventing Corneal Stromal Opacity
Yinan Liu,
Jing Hong
Abstract:Purpose:
The aims of this study were to construct a mesenchymal stem cell (MSC)-laden in situ–forming hydrogel and study its effects on preventing corneal stromal opacity.
Methods:
The native gellan gum was modified by high temperature and pressure, and the rabbit bone marrow MSCs were encapsulated before adding Ca2+ to initiate cross-linking. The effects of the hydrogel on 3D culture and gene expression of the rabbit bone marrow MSCs were observed in v… Show more
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