Mesenchymal stem cell‐derived extracellular vesicles in treatment against renal fibrosis
Jiantao Wang,
Jianxin Cui,
Shengqiang Yu
et al.
Abstract:BackgroundRenal fibrosis (RF) is the main pathological pathway of acute kidney injury and chronic kidney disease. Its main pathological feature is extracellular matrix aggregation in the renal stroma and glomerulus. There is currently no effective treatment to delay or treat RF. Mesenchymal stem cells (MSCs) are multipotent somatic stem cells that can direct differentiation, direct cell‐cell interactions and have secretory activity. The most important secretory activity of MSCs is mediated by extracellular ves… Show more
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