Merkel Cell Carcinoma of the Cheek

Abstract

Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Here, the authors reported a case of MCC, presented as a rapidly growing, asymptomatic, erythematous nodule measuring 3.8 cm × 2.8 cm in diameter on the right cheek of an 85-year-old Caucasian woman. After resection of the nodule, the defect was repaired with cutaneous graft taken from the supraclavicular area and healed uneventfully. Histopathologic examination confirmed the diagnosis of MCC.

Ischemic Damage of the Flaps: New Treatments

“…This was accompanied by improved blood perfusion in the central area of the flaps, which was determined by laser-doppler and angiography and confirmed with histological analysis. The capacity of morroniside to stimulate angiogenesis was confirmed by the increase in the number of VEGF-positive cells in the treated group, and its anti-oxidant ability was manifested by an increase in SOD activity [17,18].…”