Coccolithophores are one of the main marine primary producers in oligotrophic subtropical regions, and the largest contributors to calcium carbonate deposits on the continental slope and open ocean regions seafloor, playing an essential role in the carbon cycle. Therefore, it is important to understand the role of these organisms during periods of abrupt carbon dioxide variation, such as glacial terminations. To achieve this, the assemblages and geochemistry of coccolithophores from 150 samples of the marine core GL-854 were analyzed, covering the last 770 thousand years and eight termination periods. Gephyrocapsa spp., Florisphaera profunda, and small placoliths dominated the coccolithophore assemblage. During terminations, primary paleoproductivity estimated by coccoliths Sr/Ca ratio reached its maximum values, and larger species such as Helicosphaera spp., Calcidiscus spp., and Coccolithus pelagicus were more abundant.These periods were associated with high stratification and a stronger presence of South Atlantic Central Water in the sub-surface, increasing the percentages of F. profunda. This process occurred during high eccentricity in the Earth's orbit, intensifying seasonality and causing variations in the South Atlantic Subtropical High, allowing for intensified and more persistent northeast winds enhancing the coastal upwelling region. Along with this process, a coupling between surface-generated productivity and the transfer of this carbon to the seafloor was observed, confirming that coccolithophores are essential in the carbon cycle of oligotrophic subtropical regions, especially during transitional periods as abrupt variations in carbon dioxide. Therefore, this knowledge is essential for developing more effective biogeochemical models that can accurately predict and help mitigate carbon dioxide's impact on our environment.