Closing a branch library is a complex and often a painful activity, but one that libraries frequently face in difficult economic times. This case study examines a project that closed a branch library in an academic health sciences library system. The authors describe the sequence of steps followed, challenges encountered, and solutions implemented to complete the project. The authors document lessons learned that can benefit other libraries faced with a similar situation.I n the fall of 2008, the administration of the Western Psychiatric Institute and Clinic (WPIC) informed the Health Sciences Library System (HSLS) at the University of Pittsburgh (Pitt) that it would have to make extensive budget cuts in the collection of its library, one of four libraries the HSLS manages. In early December, after a few months of planning for space and budget reductions, the WPIC administration notified the HSLS director that WPIC Library instead would close permanently at the end of the semester. The HSLS received no reasons for the decision. Some staff positions were terminated and others retained for a few months to aid in the disposition of the collection, which was planned for completion by the end of the spring. Begun in 1942, the WPIC Library had built a comprehensive collection in psychiatry and the behavioral sciences. The HSLS staff were devastated with the decision yet had no choice but to plan to dismantle this outstanding collection.This paper is a case study on closing a departmental or branch library that is part of a larger academic library system. The library's collection was specialized, and the largest portion was unique within the system. This paper describes the planning phase, processes developed, activities, and results of the work. The authors, who served as project managers, document lessons learned that could benefit other libraries faced with a similar situation.