Mercury Toxicity and Treatment: A Review of the Literature

Bernhoft, Robin A.

doi:10.1155/2012/460508

Cited by 861 publications

(649 citation statements)

References 84 publications

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“…In a conventional treatment, to eliminate mercury from the body calcium-EDTA or penicillaminase is used, although they show a poor therapeutic effect, thus alternative natural medications could be a better solution in order to improve the protection of the environment (1,5). The propolis mechanism of action against mercury toxicity is not fully known, but it is believed that it can increase the elimination of heavy metals from the tissues through its antioxidant activity and metal chelating ability (5,7,10,21).…”

Section: Resultsmentioning

confidence: 99%

“…In contrast mercury salts tend to be insoluble, relatively stable and poorly absorbed (9). Elemental mercury has a high affinity to sulfhydryl groups and binds to glutathione or metallothioneine, and interferes with intercellular signaling and the activity of enzymes inhibiting the development of the central nervous system, stimulating the onset of neurological illnesses (1,8,9).…”

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confidence: 99%

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Influence of the administration of propolis and bee pollen preparation on the concentration of mercury in the muscles, kidneys and liver of white storks

Piedra¹,

Zienkiewicz²,

Khudhur³

et al. 2018

Medycyna Weterynaryjna

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A total of ninety white storks (Ciconia ciconia) of both sexes aged over one year of life and at a body weight between 2.8 – 4.15kg were subjects for observations. They were collected from the Warmia and Masuria region, and were rehabilitees of The Wild Birds Rehabilitation Center (Bukwald, Poland). The storks formed a group of birds that had wing damage like broken bones and were unable to fly. According to the severity of the case storks underwent three different kinds of treatment. Light cases of motion disability were submitted to wing or leg stabilization with adhesive bandages (treatment I), while middle and severe cases were additionally submitted to the administration of one (treatment II) or two capsules (treatment III) of propolis and pollen bee preparation (Apipol Farma’s Propolis Plus®) for two weeks, respectively. After the convalescence period a total of twenty three white storks did not recover and were euthanized and dissected. Post mortem samples of pectoral and femoral muscles as well as liver and kidney samples were taken. Mercury concentration was analyzed and the results revealed that the level in the kidneys and liver of white storks not receiving propolis preparation were significantly higher than that of those from treatment II and III. Contrary to this, the mercury concentration recorded in the pectoral and femoral muscles of the birds of treatment II and treatment III were significantly higher than that of the treatment without propolis preparation. The results showed that propolis and pollen bee preparation can reduce the level of mercury in kidneys and liver, but has no influence on the reduction of mercury in pectoral and femoral muscles. .

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Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Influence of the administration of propolis and bee pollen preparation on the concentration of mercury in the muscles, kidneys and liver of white storks

Piedra¹,

Zienkiewicz²,

Khudhur³

et al. 2018

Medycyna Weterynaryjna

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“…Unithiolum was chosen as it is a universal antidote in heavy metal poisoning. It contains two sulfhydryl groups and has low toxicity [4,6]. Quercetinum is nontoxic, having no cumulative effect.…”

Section: мAterials and Methodsmentioning

confidence: 99%

Status of rats myocardium under subchronic mercury exposure and its pharmacological correction

Rostislav

Sokurenko

Yuri

2016

Current Issues in Pharmacy and Medical Sciences

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The article is devoted to the characteristics of the myocardium restructuring under the influence of 0.01 LD50 mercury (II) chloride, in rats, under subchronic exposure, and the correction of the detected changes. In the work, the structural and metabolic reorganization of myocardium was studied by way of general histological, histochemical and electron microscopic techniques. Herein, administration of Unithiolum reduces the severity of reactions to toxic effects of mercury salts: decreases the intensity of inflammation in the myocardium, improves microcirculation, connective tissue and mitochondrial membranes status and reduces cardiomyocytes apoptosis. Quercetinum has a normalizing effect on the myocardium structure, reduces energy imbalance in the myocardium, and stabilizes mitochondrial membranes. Both Unithiolum and Quercetinum promote intracellular ultrastructures recovery in cardiac myocytes and in endothelial cells, and enhance the regeneration of myofibrils.

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“…Symptoms depend upon the type, dose, method, and duration of exposure. [1] We report a case of homicidal mercury poisoning as a result of ingestion of elemental mercury.…”

Section: Introductionmentioning

confidence: 99%

“…Mercury poisoning is a type of metal poisoning, due to exposure to mercury, [1] which is found in the environment in three basic states: elemental mercury or mercury vapour, inorganic mercury, and organic mercury (ethyl-, methyl-, alkyl-, or phenylmercury). [2] Mercury poisoning can occur as a result of occupational hazard or suicide attempt.…”

Section: Introductionmentioning

confidence: 99%