Mercury Poisoning Presenting With Hypertension: Report of 2 Cases

Jin, Yan; Pan, Yujie; Tang, Ziren; Song, Yuguo

doi:10.1016/j.amjmed.2019.03.050

Cited by 9 publications

(4 citation statements)

References 4 publications

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“…This condition may be associated with possible mercury exposure, since concentrations of this metal in the bloodstream are positively associated with blood pressure, hypertension, and other cardiovascular diseases. In addition, the exposure dose is an important factor in determining the effects on hypertension [ 75 , 76 , 77 ].…”

Section: Discussionmentioning

confidence: 99%

Sociobehavioral, Biological, and Health Characteristics of Riverside People in the Xingu Region, Pará, Brazil

Lucianelli

Pereira

Santos

et al. 2023

IJERPH

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This study aimed to evaluate the sociodemographic, behavioral, and biological profile and its relationship with the emergence of chronic non-communicable diseases in riverside populations in the Xingu region, Pará, Brazil. Characteristics related to health indicators and which risk factors are considered most important were analyzed. This is a cross-sectional, exploratory, and descriptive study. The sample consisted of riverside people of over 18 years of both sexes. The sample size (n = 86) was calculated with a confidence level of 95% and a sample error of 5%. The K-means clustering algorithm was adopted through an unsupervised method to divide the groups, and the values were expressed as a median. For continuous and categorical data, the Mann-Whitney and chi-square tests were used, respectively, and the significance level was set at p < 5%. The multi-layer perceptron algorithm was applied to classify the degree of importance of each variable. Based on this information, the sample was divided into two groups: the group with low or no education, with bad habits and worse health conditions, and the group with opposite characteristics. The risk factors considered for cardiovascular diseases and diabetes in the groups were low education (p < 0.001), sedentary lifestyle (p < 0.01), smoking, alcoholism, body mass index (p < 0.05), and waist–hip ratio, with values above the expected being observed in both groups. The factors considered important so as to be considered to have good health condition or not were the educational and social conditions of these communities, and one part of the riverside population was considered healthier than the other.

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Section: Discussionmentioning

confidence: 99%

Sociobehavioral, Biological, and Health Characteristics of Riverside People in the Xingu Region, Pará, Brazil

Lucianelli

Pereira

Santos

et al. 2023

IJERPH

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“…There are also some apparent systemic effects after intravenous injection, like pulmonic embolism and embolization of the heart [13,18,19]. Beyond that, Jin Yan et al [20] have documented two cases of secondary hypertension as the primary clinical manifestation of chronic contact mercury poisoning. And there are also a few cases of hemorrhagic colitis secondary to inhalation [21,22].…”

Section: Discussionmentioning

confidence: 99%

Intraorbital Mercury Removal by DSA Positioning and Route Marking: A 4-year Follow-up

Cai

Wei

Zhu

et al. 2021

Preprint

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Background: Mercury is a widely used heavy metal. Traumatic mercury residue often leads to contact dermatitis, granuloma, even chronic poisoning. Due to its unique physical and chemical properties, mercury beads can be difficult to retrieve, especially in the eyes. Most previous studies have focused only on the rigid orbital foreign bodies rather than the injuries related to liquid heavy metal and their extraction method.Methods: We reported a case of thermometer-related orbital injuries in a 4-year-old boy. To better locate, visualize and remove the mercury beads without complications, a Digital Subtraction Angiography (DSA)-guided, methylene blue marked access was taken, followed by further removal of scattered tiny mercury droplets with an adapted aspirator. Result: At least 0.7411g mercury was taken out during the surgery. After a four-year follow-up, the boy had no residual symptoms, with his urine mercury decreased gradually.Conclusion: Assessing the risk-return coefficient and making an appropriate therapeutic plan is an integral part of the pursuit of therapeutic progress. With the guidance of DSA and methylene blue, the suction of the reformative aspirator, we finally locate the mercury beads, maximize the removal of beads, reduce the length and depth of incisions, and keep the essential structures intact. Hence, we found it a valuable surgical skill on such occasions, worth sharing for future references.

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“…Increased systolic blood pressure was observed on rats undergoing chronic treatment with methylmercury chloride (MMC) ( 93 ). It has been observed that Hg can interfere with the renin–angiotensin–aldosterone system on both rats and humans, which regulates blood pressure, affecting the production and activity of these hormones ( 94 , 95 ).…”

Section: Cardiovascular Diseases and Non-essential Heavy Metalsmentioning

confidence: 99%

Non-essential heavy metal effects in cardiovascular diseases: an overview of systematic reviews

Nucera,

Serra,

Caminiti

et al. 2024

Front. Cardiovasc. Med.

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IntroductionCardiovascular diseases (CVDs) are the most important cause of premature death and disability worldwide. Environmental degradation and cardiovascular diseases are two keys to health challenges, characterized by a constant evolution in an industrialized world that exploits natural resources regardless of the consequences for health. The etiological risk factors of CVDs are widely known and include dyslipidemia, obesity, diabetes, and chronic cigarette consumption. However, one component that is often underestimated is exposure to heavy metals. The biological perspective explains that different metals play different roles. They are therefore classified into essential heavy metals, which are present in organisms where they perform important vital functions, especially in various physiological processes, or non-essential heavy metals, with a no biological role but, nonetheless, remain in the environment in which they are absorbed. Although both types of metal ions are many times chemically similar and can bind to the same biological ligands, the attention given today to nonessential metals in several eukaryotic species is starting to raise strong concerns due to an exponential increase in their concentrations. The aim of this systematic review was to assess possible correlations between exposure to nonessential heavy metals and increased incidence of cardiovascular disease, reporting the results of studies published in the last 5 years through March 2023.MethodsThe studies includes reviews retrieved from PubMed, Medline, Embase, and Web of Science databases, in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement and following the PICO (Population Intervention Comparison Outcome Population) framework.ResultsEight reviews, including a total of 153 studies, were identified. Seven of these review enlighted the association between CVDs and non-essential heavy metals chronic exposure.DiscussionIt is evident that exposure to heavy metals represent a risk factor for CVDs onset. However, further studies are needed to better understand the effects caused by these metals.

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Mercury Poisoning Presenting With Hypertension: Report of 2 Cases

Cited by 9 publications

References 4 publications

Sociobehavioral, Biological, and Health Characteristics of Riverside People in the Xingu Region, Pará, Brazil

Sociobehavioral, Biological, and Health Characteristics of Riverside People in the Xingu Region, Pará, Brazil

Intraorbital Mercury Removal by DSA Positioning and Route Marking: A 4-year Follow-up

Non-essential heavy metal effects in cardiovascular diseases: an overview of systematic reviews

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