2020
DOI: 10.1002/ppul.25122
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Mepolizumab in childhood onset steroid dependent eosinophilic granulomatosis with polyangiitis

Abstract: more data are needed before it can be implemented as standard firstline therapy.

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“…[ 5 ] To our knowledge, there are three pediatric EGPA cases successfully treated with mepolizumab in the literature. [ 6 - 8 ] In this case with relapsing and refractory myocarditis, the clinical efficacy of mepolizumab is presented without any adverse events for one year. Mepolizumab seems to be a safe treatment option in eosinophil-related end-organ inflammation for pediatric cases.…”
mentioning
confidence: 93%
“…[ 5 ] To our knowledge, there are three pediatric EGPA cases successfully treated with mepolizumab in the literature. [ 6 - 8 ] In this case with relapsing and refractory myocarditis, the clinical efficacy of mepolizumab is presented without any adverse events for one year. Mepolizumab seems to be a safe treatment option in eosinophil-related end-organ inflammation for pediatric cases.…”
mentioning
confidence: 93%