Mental health aspect of quality of life in the menopausal transition

Dotlić, Jelena; Radovanović, Saša; Rancic, Biljana; Milosevic, Branislav; Nicevic, Selmina; Kurtagic, Ilma; Marković, Nebojša; Gazibara, Tatjana

doi:10.1080/0167482x.2020.1734789

Cited by 13 publications

(15 citation statements)

References 39 publications

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“…All included intervention studies [44,46,51,53,60,63,65,74], longitudinal cohort studies [42,77] and cross-sectional studies [31,40,75,81,83,87,[100][101][102][103][104][105][106] addressing depression report an inverse association between PA and depression. Only one cross sectional-study [92] reported that regular PA before menopause was unassociated with reduced depressive feelings during perimenopause.…”

Section: Depressionmentioning

confidence: 99%

“…One study reports that menopausal status is a variable, as pre-and early perimenopausal women need a high activity level to reduce depressive symptoms, whereas postmenopausal women, at both medium and high PA levels, are associated with lower depressive symptoms than women at a low PA level [100]. Other independent variables associated with depression are marital status [101], available social support [102], subjective health status and menopausal symptoms [81,83,87], and BMI [65]. Conversely, some studies show that PA level reduces depressed mood, regardless of potential confounders [42] such as weight status, level of hot flushes [40] and physical performance [33].…”

Section: Depressionmentioning

confidence: 99%

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Psychological and social health outcomes of physical activity around menopause: A scoping review of research

Hybholt

2022

Maturitas

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Section: Depressionmentioning

confidence: 99%

Section: Depressionmentioning

confidence: 99%

Psychological and social health outcomes of physical activity around menopause: A scoping review of research

Hybholt

2022

Maturitas

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“…Post-menopause is a life period in women accompanied by reproductive senescence, including decline in ovarian sex hormones (1). Besides physical changes (2), there are many mental and psychological disorders related to post-menopausal syndrome, such as depression, anxiety or dementia (3)(4)(5)(6). The underlying mechanism of age-related cognitive decline and anxiety is unclear, but the role of estrogen loss is considered (7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

The Role of Estrogen in Anxiety-Like Behavior and Memory of Middle-Aged Female Rats

et al. 2020

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Aging in women is associated with low estrogen, but also with cognitive decline and affective disorders. Whether low estrogen is causally responsible for these behavioral symptoms is not clear. Thus, we aimed to examine the role of estradiol in anxiety-like behavior and memory in rats at middle age. Twelve-month old female rats underwent ovariectomy (OVX) or were treated with 1 mg/kg of letrozole-an aromatase inhibitor. In half of the OVX females, 10 µg/kg of 17β-estradiol was supplemented daily for 4 weeks. Vehicle-treated sham-operated and OVX females served as controls. For behavioral assessment open field, elevated plus maze and novel object recognition tests were performed. Interaction between ovarian condition and additional treatment had the main effect on anxiety-like behavior of rats in the open field test. In comparison to control females, OVX females entered less frequently into the center zone of the open field (p < 0.01) and showed lower novel object discrimination (p = 0.05). However, estradiol-supplemented OVX rats had higher number of center-zone entries (p < 0.01), spent more time in the center zone (p < 0.05), and showed lower thigmotaxis (p < 0.01) when compared to OVX group. None of the hormonal manipulations affected anxiety-like behavior in the elevated plus maze test significantly, but a mild effect of interaction between ovarian condition and treatment was shown (p = 0.05). In conclusion, ovariectomy had slight negative effect on open-field ambulation and short-term recognition memory in middle-aged rats. In addition, a test-specific anxiolytic effect of estradiol supplementation was found. In contrast, letrozole treatment neither affected anxiety-like behavior nor memory.

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“…This is a series of objective and subjective elements that are related to life expectations. When women have high levels of life satisfaction, this generally correlates with a higher HRQL [9][10][11]. Social support, which includes characteristics such as having people to communicate with and emotional support or displays of affection, love and empathy, has a considerable impact on HRQL [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Holistic Quality of Life in Women during Natural Perimenopause and Postmenopause

María¹,

Evelia²

2020

Act Sci wom hea

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The goal of the present study was to assess the health status of women during the natural climacteric with respect to physical, mental, and social variables. Design: It is a descriptive correlational study. Setting 419 perimenopausal women are involved on a voluntary basis. 273 women were premenopausal and 146 were postmenopausal. The tools used were the GHQ-12 General Health Questionnaire, and Duke-UNC-11 Questionnaire of Functional Social Support. Results: It was found that the youngest women tended to suffer from anaemia more often, and that the oldest women suffered from osteoporosis, osteoarthritis and arthritis. It was also found that postmenopausal women had better mental health. Regarding social support, there were no statistically significant differences between the two groups of women. With respect to holistic quality of life, it was found that the youngest women enjoyed better living conditions. Conclusion: This study provides insight into the health of women during the natural climacteric, and a gender perspective with respect to health research with the aim of removing the possibility of health discrimination by gender.

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Mental health aspect of quality of life in the menopausal transition

Cited by 13 publications

References 39 publications

Psychological and social health outcomes of physical activity around menopause: A scoping review of research

Psychological and social health outcomes of physical activity around menopause: A scoping review of research

The Role of Estrogen in Anxiety-Like Behavior and Memory of Middle-Aged Female Rats

Holistic Quality of Life in Women during Natural Perimenopause and Postmenopause

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