Mental disorder and the outcome of HIV/AIDS in low-income and middle-income countries

Mayston, Rosie; Kinyanda, Eugene; Chishinga, Nathaniel; Prince, Martin; Patel, Vikram

doi:10.1097/qad.0b013e32835bde0f

Cited by 144 publications

(123 citation statements)

References 40 publications

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“…A systematic review found that alcohol users were more likely to have missed at least one or more cascades of continuum of care such as attending treatment services, ART compliance, routine investigation of viral loads, and CD4 count [20]. Additionally, alcohol users also engage in substance use as a coping mechanism for reducing stress related to HIV, which further deteriorates their health [21]. …”

Section: Introductionmentioning

confidence: 99%

Harmful alcohol drinking among HIV-positive people in Nepal: an overlooked threat to anti-retroviral therapy adherence and health-related quality of life

Pokhrel

Pokhrel²,

Neupane³

et al. 2018

Global Health Action

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Background: People living with Human Immunodeficiency Virus (HIV) often suffer from alcohol-use disorders resulting in their poor health and treatment outcomes. Little is known about the association of harmful alcohol drinking with their adherence to anti-retroviral therapy (ART) and health-related quality of life (QOL) in low-resource settings. Objective: This study aimed to investigate associations between harmful alcohol drinking, adherence to ART and health-related QOL in HIV-positive people, stratified by gender, in Nepal. Methods: We conducted a cross-sectional study of 682 HIV-positive people on ART to measure their self-reported harmful alcohol drinking and non-adherence to ART in the previous month of data collection. We also measured health-related QOL using a WHOQOL-HIV BREF scale. The association between harmful alcohol drinking and non-adherence to ART was examined using multiple logistic regressions. Additionally, multiple linear regressions examined association between harmful alcohol drinking and QOL. Results: Harmful alcohol drinking was associated with non-adherence to ART among men (AOR: 2.48, 95% CI: 1.50, 4.11, p < 0.001) and women (AOR: 2.52, 95% CI: 1.32, 4.80, p = 0.005). Men were more likely to have lower score for the psychological (β = −0.55, p = 0.021) and level of independence (β = −0.68, p = 0.018) domains when they had harmful alcohol drinking. Moreover, women were more likely to have lower scores for the physical (β = −1.01, p = 0.015), social relations (β = −0.82, p = 0.033), environmental (β = −0.88, p = 0.011), and spiritual (β = −1.30, p = 0.005) domains of QOL when they had harmful alcohol drinking. Conclusions: Harmful alcohol drinking had a negative association with ART adherence and QOL in both HIV-positive men and women in Nepal. Screening for alcohol-use disorders and community-based counseling services should be provided while delivering ART services to improve treatment adherence and QOL.

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Section: Introductionmentioning

confidence: 99%

Harmful alcohol drinking among HIV-positive people in Nepal: an overlooked threat to anti-retroviral therapy adherence and health-related quality of life

Pokhrel

Pokhrel²,

Neupane³

et al. 2018

Global Health Action

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“…When population based screening occurs, CMDs can be identified at higher rates in PLHIV compared to the general population [7][8][9]. WHO guidelines underscore that PLHIV in resource-limited settings may experience CMDs, and that HIV care settings provide the opportunity to screen for and manage common CMDs through a range of care and treatment options that include counseling and pharmacotherapy [9,10] Depression and anxiety are common CMDs observed among PLHIV, particularly women [11][12][13][14][15].…”

Section: Common Mental Disorders and Hiv Infection In Low And Middle mentioning

confidence: 99%

“…These models seek to increase the quality of HIV service delivery in clinics for those PLHIV who have more medical needs. PLHIV with CMDs and SUDs often have multiple co-morbidities along with medical and social needs that require complex medical and support services for good clinical outcomes [92,93]. Thus, the alternative models of HIV service delivery are a positive step in addressing the needs of PLHIV with CMDs and SUDs, if the needed services for these PLHIV are accessible and available.…”

Section: Services For Common Mental Disorders and Substance Use Disormentioning

confidence: 99%

Incorporating services for common mental disorders and substance use disorders for people living with HIV along the HIV treatment cascade

Kresina¹,

Lapidos‐Salaiz²,

Lopez³

et al. 2017

Ment Health Addict Res

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“…Por un lado, los TCS comprometen la respuesta al tratamiento de los demás trastornos mentales y las enfermedades infecciosas (Dausey & Desai, 2003;King et al, 2000;Mayston, Kinyanda, Chishinga, Prince, & Patel, 2012); pero por el otro, se ha documentado que contar con una enfermedad infecciosa también tiene consecuencias en la salud mental de quienes la padecen (por ejemplo exacerbación de síntomas depresivos, distrés psicológico y problemas de sueño) (Collins, Holman, Freeman & Patel, 2006;McCabe et al, 2014).…”

Section: Implicaciones De Salud Públicaunclassified

“…Finalmente, se ha documentado que los trastornos mentales dificultan la adherencia al tratamiento retroviral, especialmente en países de mediano y bajo ingreso (Collins et al, 2006;Mayston et al, 2012).…”

Section: Implicaciones De Salud Públicaunclassified

Patología dual en poblaciones especiales: una revisión narrativa

Szerman¹,

Marín-Navarrete²,

Fernández-Mondragón³

et al. 2015

RIIAD

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RESUMENIntroducción: la patología dual se refiere a la concurrencia de un trastorno por consumo de sustancias con otro trastorno psiquiátrico. Estudios epidemiológicos en población general reportan una alta prevalencia de patología dual. Sin embargo, la información disponible sobre el tema en poblaciones especiales es limitada. Objetivo: revisar la evidencia disponible sobre la epidemiología, la atención y los aspectos relevantes para la salud pública acerca de la patología dual en las siguientes poblaciones especiales: personas en situación de indigencia, en prisión, con VIH, VHB y VHC, mujeres y adultos mayores. Método: búsqueda en bases de datos bibliográficos (PubMed, Science Direct, EBSCO y OVID) de reportes de investigación enfocados en la prevalencia y el tratamiento de patología dual en las poblaciones mencionadas. Resultados: la prevalencia de la patología dual se presenta de manera diferenciada en estas poblaciones, en comparación con la población general; además está altamente asociada con mayores tasas de morbilidad y mortalidad. La mayoría de los estudios específicos sobre patología dual y las poblaciones especiales, tanto de epidemiología como de tratamientos, se ha realizado en países de alto ingreso. Discusión y conclusiones: se requiere de políticas públicas que contemplen la medición epidemiológica de la patología dual en estas poblaciones, sobre todo en países de mediano y bajo ingreso, e incluyan intervenciones integradas adecuadas a las necesidades específicas de cada población.Palabras clave: patología dual; grupos minoritarios; epidemiología; revisión. ABSTRACTBackground: dual disorders is a term that refers to the co-occurrence of a substance use disorder with other mental disorders. Epidemiological studies have reported a high prevalence of dual disorders in the general population. However, information on dual disorders in special population is limited. Objective: to give an overview of the available evidence on the epidemiology, care and other relevant aspects for public health of dual disorders in the following special populations: homeless, prison inmates, people with sexually-transmitted infections, and the elderly. Method: search in peer-review publication databases (PubMed, Science Direct, EBSCO and OVID) for research reports on the epidemiology and treatment of dual pathology in the aforementioned populations. Results: prevalence of dual disorders in these populations appears to be different than in the general population; and it is highly associated with higher mortality and morbidity rates. The majority of studies aimed specifically on the epidemiology and treatment of dual disorders and special populations has been conducted in high-income countries. Discussion and conclusions: there is a need for public policies that consider the epidemiological assessment of dual disorders in special populations, specially in low-and middle-income countries, and include integrated care interventions adequate to the specific needs of each population.

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Mental disorder and the outcome of HIV/AIDS in low-income and middle-income countries

Cited by 144 publications

References 40 publications

Harmful alcohol drinking among HIV-positive people in Nepal: an overlooked threat to anti-retroviral therapy adherence and health-related quality of life

Harmful alcohol drinking among HIV-positive people in Nepal: an overlooked threat to anti-retroviral therapy adherence and health-related quality of life

Incorporating services for common mental disorders and substance use disorders for people living with HIV along the HIV treatment cascade

Patología dual en poblaciones especiales: una revisión narrativa

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