Menopause, skin and common dermatoses. Part 4: oral disorders

Ashraf, Mariha; Kamp, Erin; Musbahi, Esra; DeGiovanni, Claudia

doi:10.1111/ced.15341

Cited by 3 publications

(2 citation statements)

References 29 publications

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“…The decrease in collagen in women is calculated at 2.1% per year [5,61]. These variations cause various atrophies, which not only concern the genitourinary system but also the skin in general, becoming less elastic and dehydrated; this causes an increase in wrinkles and itchy sensations, and arthralgia also occurs at the distal joints (knees, hip, and spine); the incidence is 50% [11,62]. Many studies have shown that with the hormonal changes of menopause, sexual desire in women decreases.…”

Section: Menopause-associated Symptoms and Diseasesmentioning

confidence: 99%

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Comparetto,

Borruto

2023

OBM Geriatr

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In the United States (US), menopause occurs at an average age of 52. Menopausal symptoms tend to be maximal during the few years before and the year after menopause (during perimenopause), except for symptomatic vulvovaginal atrophy, which may worsen over time. Up to 20% of bone density loss occurs during the first 5 years after menopause, followed by an age-related bone loss rate similar to that in men. Menopause should be considered confirmed if an age-appropriate woman who is not pregnant has not had a menstrual period for 12 months. Regarding treatment, for vaginal dryness or dyspareunia due to menopause, vaginal stimulation and vaginal lubricants and moisturizers are recommended, and if these are ineffective, low-dose vaginal estrogen, in the form of creams, tablets, suppositories, or rings should be considered; other options include oral ospemifene or intravaginal dehydroepiandrosterone (DEHA) suppositories. Before prescribing hormone replacement therapy (HRT) and periodically while therapy continues, women should be informed of risks (e.g., deep vein thrombosis [DVT], pulmonary embolism [PE], stroke, breast cancer, gallbladder disease, and urinary incontinence); potential harms are greatest for women who start HRT after 60 years of age or who are 10-20 years past menopause onset. If women choose HRT to relieve hot flushes, estrogen plus, a progestin or conjugated estrogen/bazedoxifene could be prescribed for women who still have the uterus. Treatment with HRT should be tailored to maximize benefits and minimize harms, and periodically benefits and harms should be reassessed; low-dose transdermal HRT may lead to a lower risk of DVT and stroke. Selective serotonin reuptakereuptake inhibitors (SSRIs), selective serotonin-nor-epinephrine reuptake inhibitors (SNRIs), and gabapentin could be considered as less effective alternatives to HRT for relieving hot flushes; paroxetine 7.5 milligrams (mg) is the only non-hormonal drug approved in the US for the relief of hot flushes. Effective non-drug options include cognitive behavioral therapy and hypnosis.

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Section: Menopause-associated Symptoms and Diseasesmentioning

confidence: 99%

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Comparetto,

Borruto

2023

OBM Geriatr

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“…We also identified that the majority of BMS patients were women. The age and sex characteristics of BMS hint at two main points: (1) age and body changes that could include the susceptibility to dry skin by the nature of decreased water content and overall drier skin [52] and (2) hormonal changes during the menopausal years of the affected women [53]. Lower estrogen levels could lead to not only skin dryness and thinning but also other skin concerns, such as decreased skin elasticity, firmness, wrinkles, and age spots [54].…”

Section: Demographic Characteristicsmentioning

confidence: 99%

Is Burning Mouth Syndrome Associated with Extraoral Dryness? A Systematic Review

Le,

DosSantos,

Gazerani

2023

JCM

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Burning mouth syndrome (BMS) is characterized by a persistent intraoral burning sensation, often experienced by postmenopausal women. The etiology of BMS remains partially understood, and consequently, treatments remain suboptimal. Extraoral manifestations of BMS, such as extraoral dryness, are less studied. However, it has been suggested that the identification of the frequency and patterns of extraoral dryness and potential underlying mechanisms are essential to optimize treatment strategies and reduce the burden of disease. Therefore, we conducted this systematic review to provide existing evidence about extraoral dryness in BMS. The guidelines for the conduction and reporting of systematic reviews were followed. An electronic search was conducted in four major databases—PubMed, Web of Science, COCHRANE Library, and EBSCOhost—and the grey literature was assessed through Google Scholar. From each included article, information on extraoral dryness in BMS was extracted, and odds ratios were calculated for extraoral dryness among BMS patients compared with non-BMS controls. The findings demonstrated higher odds of the prevalence of extraoral dryness in BMS, which was found to a high degree in the lips, eyes, skin, and genitalia. The pattern of spread and locations of extraoral dryness propose a potential central mechanism. Based on our findings, we encourage the standardization of the assessment, recording, and reporting of the extraoral characteristics of BMS, including extraoral dryness, which can lead to better management strategies and enhance the quality of life of the affected patients.

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Burning mouth syndrome in menopausal women

Maksimova

2024

Rus. Jour. of Pain

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Menopause, skin and common dermatoses. Part 4: oral disorders

Cited by 3 publications

References 29 publications

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Is Burning Mouth Syndrome Associated with Extraoral Dryness? A Systematic Review

Burning mouth syndrome in menopausal women

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