Menopause Hormone Replacement Therapy and Lifestyle Factors affect Metabolism and Immune System in the Serum Proteome of Aging Individuals
Clemens Dierks,
Roza Sürme Mizrak,
Orr Shomroni
et al.
Abstract:Aging is a fundamental risk factor for a wide array of diseases. The Berlin Aging Study II (BASE-II) is a cohort study designed to investigate the physical, mental, and social determinants of successful aging. We utilized high-throughput mass spectrometry to measure the proteomes of 1890 BASE-II participants, divided into two age groups: 27-37 years and 60-85 years. We employed multiple linear regression analyses to explore the effects of demographic factors such as age, sex, and BMI, along with hormonal treat… Show more
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