Menopause: A Global Perspective and Clinical Guide for Practice

Voedisch, Amy; Dunsmoor-Su, Rebecca; Kasirsky, Jennifer

doi:10.1097/grf.0000000000000639

Cited by 18 publications

(18 citation statements)

References 62 publications

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“…It is classified into premenopausal, perimenopausal, and postmenopausal stages, defined based on endocrine status and regularity of menstrual bleeding pattern (Harlow et al, 2012). Menopause manifests in women aged between 46 and 52 years, signaling the end of reproductive life due to ovarian follicular exhaustion (Voedisch et al, 2021). The absence of complete menstruation defines this condition as being considered early before age 40 and late after age 55.…”

Section: Introductionmentioning

confidence: 99%

A hydroalcoholic blackberry leaf extract improved glucose tolerance and body composition and attenuated depression-like symptoms in ovariectomized rats.

Mendes

Figueiró²,

Nunes³

et al. 2023

RSD

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Blackberry leaves (Morus nigra) are used in menopause to relieve hot flashes and night sweats and have been investigated in metabolic disorders. However, few studies investigated its effects on metabolic and behavioral disorders when associated with menopause. This study evaluated the effects of a hydroalcoholic extract of M. nigra leaves (MN) on body composition, glucose tolerance, and depression and anxiety-like behaviors in ovariectomized rats. For this purpose, 36 female Wistar rats were divided into groups: C – control; COvx – ovariectomized; MNOvx – ovariectomized and given MN at 400 mg.kg-1 body mass/day. Body composition was assessed by DEXA, glucose tolerance by the oral glucose tolerance test, and depression and anxiety-like behaviors by the forced swimming and elevated plus maze tests, respectively. Food intake and body mass gain were higher for MNOvx, followed by COvx and C (p<0.05). The MNOvx group gained less body fat than COvx (p<0.05) and was more glucose tolerant compared to C and COvx (p<0.05). In the elevated plus maze, COvx and MNOvx remained for less time in the open arms and longer in the closed arms than C (p<0.05). In forced swimming, immobility time was higher for COvx, followed by C and MNOvx (p<0.05). The MN protected ovariectomized rats from body fat gain, improved glucose tolerance, and attenuated depression-like behavior. Phytoestrogens and other bioactive compounds in MN may be involved in these effects.

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Section: Introductionmentioning

confidence: 99%

A hydroalcoholic blackberry leaf extract improved glucose tolerance and body composition and attenuated depression-like symptoms in ovariectomized rats.

Mendes

Figueiró²,

Nunes³

et al. 2023

RSD

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“…This situation can lead to the patient's desire for the preservation of fertility. In addition, standard surgery of EOC in the reproductive age group causes early menopause, which can result in numerous health problems 4 . In the early stages of a disease, fertility‐sparing surgery (FSS) is an option for women who wish to preserve their reproductive functions; it can also help avoid early menopause.…”

Section: Introductionmentioning

confidence: 99%

Oncologic and obstetric outcomes of early‐stage epithelial ovarian cancer patients who underwent fertility‐sparing surgery: A retrospective study

Ayhan

Tunç

Karakaş

et al. 2023

Intl J Gynecology & Obste

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Ovarian carcinoma is the second most common gynecological cancer, and most ovarian malignancies are derived from epithelial cells. 1 Although epithelial ovarian cancer (EOC) is commonly seen in the postmenopausal era, as many as 17% of patients with EOC are in the reproductive era at the time of diagnosis. 2 Standard treatment of EOC is staging surgery, which consists of total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic and paraaortic lymphadenectomy, peritoneal biopsies, adjuvant chemotherapy-a combination therapy of platinum/taxane derivatives-and, finally, targeted therapies for high-grade histology and/or advanced stages. 3 Two or three decades ago, EOC treatment comprised comprehensive surgery and adjuvant chemotherapy only aiming to

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“…In turn, this has resulted in far larger numbers of women reaching menopause than ever before making the menopause an issue of growing global importance. As such, the review by Voedisch et al9 is both timely and highly relevant. In fact their review is a veritable tour-de-force of both epidemiological and clinical menopausal perspectives.…”

mentioning

confidence: 99%

Foreword: Global Gynecology

Blumenthal¹

2021

Clinical Obstetrics &Amp; Gynecology

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In this issue of Clinical Obstetrics and Gynecology, the first to center on global issues in gynecology, we present a raft of papers that focus on topics central to women's health globally, and which review the principle causes of morbidity and mortality among women worldwide. Indeed, while, for decades, the thrust of international programming, research, and advocacy, has been directed toward maternal mortality reduction, the fact is that the various clinical issues presented here account for the vast remainder of women's morbidity and mortality beyond maternity. Issues such as unmet need for contraception, unsafe abortion, cervical cancer prevention, sequelae of obstetrical fistula, human immunodeficiency virus (HIV) incidence and management, female genital cutting (FGC), and menopause are currently at the core of both current global programming and research, and while many of these areas remain grossly underfunded compared with maternal mortality, considerable progress has been made towards improving the quality, duration and safety of women's lives worldwide, particularly in lower-income and middle-income countries (LMICs).In a commentary parallel to this foreword, Dame Professor Lesley Regan, former President of the Royal College of Obstetricians and Gynaecologists and a renowned advocate for reproductive justice and equity in access to reproductive health care, and her coauthor Jenny Summerfield contribute a compelling assessment of progress (or lack thereof) towards achieving the Millennium Development Goals, specifically Sustainable Development Goal 5 aimed at empowering women and girls to achieve gender equity for both health care initiatives and full integration as part of their national social fabric. Their paper provides a lucid and logical link to considerations of maternal mortality, indicating that many of the issues discussed in this gynecologically focused edition of Clinical Obstetrics and Gynecology are part of a continuum of care seamlessly connected to maternal morbidity and mortality.Contraceptive technologies and family planning programs are consummate examples of primary prevention. In fact, in parallel to the current global experience connected to coronavirus disease (COVID) 19, one could consider all family planning programs to be "immunization" programs of sorts. In essence, given current technologies, birth controlThe author declares that there is nothing to disclose.

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Menopause: A Global Perspective and Clinical Guide for Practice

Cited by 18 publications

References 62 publications

A hydroalcoholic blackberry leaf extract improved glucose tolerance and body composition and attenuated depression-like symptoms in ovariectomized rats.

A hydroalcoholic blackberry leaf extract improved glucose tolerance and body composition and attenuated depression-like symptoms in ovariectomized rats.

Oncologic and obstetric outcomes of early‐stage epithelial ovarian cancer patients who underwent fertility‐sparing surgery: A retrospective study

Foreword: Global Gynecology

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