Meningoencefalitis por Loa loa secundaria a tratamiento con mebendazol

Imported Loa loa filariasis: three cases and a review of cases reported in non-endemic countries in the past 25 years

“…Moreover, one case of encephalopathy with delirium and a case of meningoencephalitis were described following treatment with albendazole and mebendazole. 74,92 A follow-up period was reported for only 35 (34.7%) patients overall (including our three patients) for a length of time ranging from 1 to 84 months (median 10.5 months) 7,12,14,16,17,23,25,44,[47][48][49]58,63,65,66,68,69,[73][74][75]79,81,82,84,88,90,91 (and PR). With the exception of four patients, one of whom had a relapse of microfilaremia 3 months after the end of treatment, 16 one with persistence of microfilaremia 2 months later, 91 and two patients with the recurrence of symptoms, 25,73 the remaining 31 patients remained asymptomatic during the follow-up.…”

“…The African country of acquisition of loiasis was not specified in nine cases; 8,11,14,16,29,49,61,73,89 56 Cameroon and Congo, 59 and Cameroon, Nigeria, and Niger 66 ). Microfilaremia was more common in immigrants (78.0%) 7,13,[21][22][23]26,31,35,37,39,40,47,48,52,58,61,63,67,70,74,75,80,82,[85][86][87][88]91,92 (including PR cases) than in expatriates and travelers (Table 3). In contrast, peripheral blood eosinophilia (95.3%) [8][9][10][11][12]14,16,[18]…”