Meningococcal septicaemia reported in an immunocompetent adult: A Case Report

Abstract

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Case series of meningococcal sepsis; are we seeing the real picture

“…It is a major cause of bacterial meningitis globally and of significant public health concern due to high mortality, morbidity and ability to create outbreaks. 1,2,3 The fatality rate is about 13% even with treatment whereas without treatment it rises up to 50%-90% and 3%-4% of survivors suffer from complications. 3 This case series of invasive meningococcal disease is the first and largest reported in Sri Lanka which highlights an impending serious health problem for our community.…”

“…The detection of antigen or DNA of N. meningitidis from sterile site also confirms the disease. 2,6,7 Gram staining of blood, CSF and skin aspirates facilitates early identification of patients for targeted therapy. All our patients had meningococcemia and their meningococcal isolates were subsequently confirmed by biochemical tests and PCR.…”

“…Meningococcal sepsis is not commonly reported in Sri Lanka. Only a few cases have been reported 1,2 , and this is the largest case series managed in Sri Lanka. Invasive disease due to Neisseria meningitidis is a medical emergency.…”