Meningococcal Brain Abscess and Meningitis in a Neonate

Rapid sterilisation of cerebrospinal fluid in meningococcal meningitis: Implications for treatment duration

“…There is anecdotal evidence that neonates in particular do not handle this infection well and there is a high morbidity and mortality in this subgroup. [22][23][24] We believe, as is recommended elsewhere, that children under 3 months should receive conventional length therapy until more data are available.…”

Bacterial Sepsis and Meningitis

“…The infant can be infected at delivery by organisms present in the maternal genital tract, or intrauterine infection can result during maternal meningococcemia [182]. Meningococcal sepsis is rare in neonates, but more than 50 cases (including 13 from the preantibiotic era) have been described [183][184][185]. Earlyonset and late-onset forms [178,179,185] of meningococcal sepsis in neonates have been reported.…”

Early onset neonatal infection with Neisseria meningitidis serogroup C: case report and literature review

“…Based on the definition, early onset of neonatal meningococcal disease is extremely rare as evidenced by the paucity of reports in the literature (Table 1). To our knowledge, only 11 cases (including the one described here) have been reported to date [2,3,4,6,7,8,10,11]. One case was reported from the pre-antibiotic era and the other ten cases were reported from the antibiotic era.…”

“…A few cases of early onset neonatal infection with N. meningitidis have been reported [2,3,4,6,7,8,10,11], and only two had onset of symptoms from the time of birth [2,7]. We describe a neonate with N. meningitidis C sepsis who was ill from birth and review the literature for previously reported cases of early onset neonatal infection caused by N. meningitidis.…”