Meningitis in Children: A Study in Medical College &amp; Hospital, Kolkata

Joardar, Swarnali; Joardar, Gautam Kumar; Mandal, Pankaj Kumar; Mani, Siddhartha

doi:10.3329/bjch.v36i1.13031

Cited by 10 publications

(8 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The hot, dry seasonal increase in admission and male predominance was consistent with other studies from Bangladesh [13] and BurkinaFaso [14]; but not similar to previous studies from Gondar [4] and Addis Abeba [3]. The preponderance of the under-fives underscores the age group that bears the brunt of the disease burden.…”

Section: Discussionsupporting

confidence: 87%

Epidemiology of bacterial meningitis in children admitted to Gondar University Hospital in the post pneumococcal vaccine era

Amare¹,

Kebede²,

Welch³

2018

Pan Afr Med J

View full text Add to dashboard Cite

Introduction Community acquired bacterial meningitis (CABM) is responsible for high mortality and disabling sequelae. Introduction of pneumococcal conjugate vaccine (PCV-10) and haemophilus influenzea type b (Hib) has changed the epidemiological and clinical features of patients presenting with CABM as it is shown in different literatures over the last decade. The aim of this study was to assess the clinical and epidemiologic features and outcomes of CABM after the introduction of PCV-10 in Gondar University Hospital (GUH). Methods This is a retrospective study among children between 2 months and 14 years of age discharged from Gondar University Hospital. All patient records discharged with a diagnosis of meningitis at GUH were reviewed from September 2011 - September 2013. The data was collected using a structured questionnaire from the patient record charts and analysis was done using SPSS-20. Results 80 cases (1.6%) of CABM out of 4996 admissions were identified. There were 60 (75%) cases of CABM using WHO criteria of cerebrospinal fluid leukocytosis (CSF) > 100cells/mm 3 , or 10-100cells/mm 3 with either hypoglycorrhea or increased protein; and 20 (25%) with culture confirmation. S. Pneumoniae was the most frequent pathogen identified in 14 (70%) children. The most common age group were infants 2-12 month old (n = 32, 40%). Children with adverse outcomes had shown a higher frequency of being older children (p = 0.045), loss of consciousness (p = 0.046), seizure at admission (p < 0.01), and a positive CSF culture (p = 0.03). Conclusion Introduction of PCV-10 has shown a decreased admission rate, mortality, and neurologic sequelae due to CABM.

show abstract

Section: Discussionsupporting

confidence: 87%

Epidemiology of bacterial meningitis in children admitted to Gondar University Hospital in the post pneumococcal vaccine era

Amare¹,

Kebede²,

Welch³

2018

Pan Afr Med J

View full text Add to dashboard Cite

show abstract

“…The overall case fatality rate (CFR) is 9.7%, similar to another study [25,11]. CFR observed in this study is lower than 31.29% reported in a study carried out in India [26] and 18.5% in Cameron [17]. However, there are various factors affecting the outcomes such as age, severity of the disease, virulence of the infecting microorganisms, time elapsed since the onset of disease till a specific antibiotic administration and quality of care [26].…”

Section: Discussionsupporting

confidence: 81%

“…CFR observed in this study is lower than 31.29% reported in a study carried out in India [26] and 18.5% in Cameron [17]. However, there are various factors affecting the outcomes such as age, severity of the disease, virulence of the infecting microorganisms, time elapsed since the onset of disease till a specific antibiotic administration and quality of care [26]. In the present study the majority of deaths occurred for children under a year, and thus the risk factors of death noticed in this study are: younger age < 12 months, delay in starting medication > 3 days since the onset of disease, presence of S pneumonia causing meningitis and severe degree of symptoms at time of hospitalization.…”

Section: Discussioncontrasting

confidence: 80%

Epidemiology and Outcome of Acute Bacterial Meningitis Among Children in Saudi Haospital Hajjah, Northwest Territories of Yemen

Alshehari¹,

Al-Selwi²,

Albahloly³

2018

AJP

View full text Add to dashboard Cite

This is a retrospective descriptive study carried out in Saudi Hospital Hajjah between July 2016 and December 2017: The aim of this study is to assess the etiology and outcome of acute bacterial meningitis among children in Saudi Hospital Hajjah. We included in this study all children aged one month or more to 12 years who had symptoms and signs suggested acute bacterial meningitis confirmed by lumber puncture of cerebrospinal fluid for cells, biochemistry and culture. The data of all patients were retrieved from the hospital records and patient`s charts. These data included age, clinical presentation, etiologic microorganism and outcome. A total of 196 patients who had confirmed bacterial meningitis was recorded. Of these, 71 patients (36.2%) were aged under 12 months, 25% aged between 1-2 years old, 17.9% between 3-5 years and 20.9% > 5 years. Cerebrospinal fluid culture was positive among 94.9% of patients. Among the positive isolates, 43.5% were having Nesseria meningitidis, 34.9% Streptococcus pneumonia, 18.2% Hemophillus influenza type b, 2.7% group B Streptococci and 0.5% E.coli. There were 19 patients died giving the case fatality rate as 9.7%. Of those, 47.3% had aged less than 12 months, 31.5% aged 1-2 years, one child (5.2%) aged 4 years and 3 cases (15.8%) were > 5 years. Eleven cases of deaths (57.9%) had s. pneumonia infections. There were 24 patients (12.2%) of survivors developed neurological complications. This study demonstrates that there is no change in the epidemiology of the main causes of acute bacterial meningitis among children compared to that reported prior to introduction Hib and pneumococcal vaccines indicating a limited coverage of vaccination in the Northwest Territories of Yemen. The case fatality rate noted in this study is relatively low, but aggressive efforts by the health care system both to vaccinate and to early treat infected children, meningitis incidence and mortality will decline.

show abstract

“…In Joardar et.al study 34.66% were pyogenic according to causative agents. 17 Another survey in India showed that there is increased prevalence of Pyogenic meningitis in males as compared to females. 18 A similar survey was carried out in Nigeria 19 which showed that males are affected in 70% of cases whereas females are affected in 30% of cases while current study reported 57.29% were male and 42.71% were female.…”

Section: Resultsmentioning

confidence: 99%

Prevalence of pyogenic meningitis in a Tertiary Care Hospital of Sindh.

Siyal

Jamali

Qambrani

2020

TPMJ

View full text Add to dashboard Cite

Objectives: The current study aimed to find out the prevalence of pyogenic meningitis in the local population of Peoples University of Medical and Health Sciences Hospital Nawabshah. Study Design: Descriptive Cross Sectional study. Setting: Pediatric Ward of People University of Medical and Health Sciences Hospital, Nawabshah. Period: 1 year from November 2018 to October 2019. Material & Methods: Using self-designed questionnaire. Patient’s samples were send for relevant investigations i.e. Blood culture and CSF examination and their results were recorded in proforma. Statistical Package for Social Science (SPSS) version 21 was used for data analysis. Results: Mean age of the children was 7 Years with a standard deviation of 2.4 years. 57% of the sample consist of boys while 43% were girls. Diagnosis of pyogenic meningitis was confirmed in 52.08% of the cases and fever was present in 100% cases and was the most common clinical presentation followed by headache (67%), Vomiting (44%) and fits (28%). Mean protein level was 235 mg/dl in the diagnosed cases. Mean sugar level in CSF of diseased children was 35 mg/dl with significant p-value of 0.0005. Conclusion: Pyogenic meningitis is highly prevalent that is 52.08% in current study. Its morbidity and mortality can be reduced by early recognition and prompt treatment.

show abstract

Meningitis in Children: A Study in Medical College & Hospital, Kolkata

Cited by 10 publications

References 9 publications

Epidemiology of bacterial meningitis in children admitted to Gondar University Hospital in the post pneumococcal vaccine era

Epidemiology of bacterial meningitis in children admitted to Gondar University Hospital in the post pneumococcal vaccine era

Epidemiology and Outcome of Acute Bacterial Meningitis Among Children in Saudi Haospital Hajjah, Northwest Territories of Yemen

Prevalence of pyogenic meningitis in a Tertiary Care Hospital of Sindh.

Contact Info

Product

Resources

About