Meningitis aséptica por virus parotídeo asociada a la vacuna

L, Aline Jorquera; C, Daniela Ugarte; L, Carmen Avilés; M., Luis Delpiano

doi:10.4067/s0716-10182020000600769

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…7 The waning of vaccination is one of the major risk factors for the development of viral mumps which was also reported by Jorquera et al in an older infant diagnosed with aseptic meningitis and viral mumps after 3 weeks of receiving the MMR vaccination. 9 Such rare cases reflect the importance of waning vaccination for viral mumps and propose a need for future research and studies to evaluate the factors responsible for waning and to develop preventative methods for such outbreaks.…”

Section: Discussionmentioning

confidence: 99%

Aseptic meningitis rare complication of mumps in an adult

et al. 2022

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Mumps is endemic worldwide, with epidemics every 3-5 years in unvaccinated populations. After the introduction of the mumps vaccine in the national immunization schedule, the number of reported cases declined by >97% in 1989 until an outbreak of 6584 cases was reported in 2006 even in populations with high-level vaccination coverage and all the patients had a history of vaccination. Here we present a case of mumps with aseptic meningitis in a 42-year-old female. Although historically mumps was a disease of childhood, with most cases occurring in children 5-9 years of age, mumps now most frequently occur in older age groups. This shift in age distribution and the occurrence of mumps in the vaccinated population suggest a waning of vaccine immunity.

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Section: Discussionmentioning

confidence: 99%

Aseptic meningitis rare complication of mumps in an adult

et al. 2022

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Aseptic meningitis following AZD1222 COVID-19 vaccination

Zavari¹,

Hamidabad²,

Hassanzadeh³

2022

The American Journal of Emergency Medicine

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The AZD1222 is one of the vaccines used against coronavirus disease 2019 (COVID-19), which is currently being used in many countries worldwide. Some important neurological side effects have been reported in association with this vaccine, but aseptic meningitis has not yet been reported. Herein, we report a case of aseptic meningitis in a 26-year-old health care worker, following the first dose of the AZD1222 vaccine.

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Evaluation of patients presenting with febrile seizures in an Iranian referral hospital: emphasis on the frequency of meningitis and co-infections

et al. 2023

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Introduction Febrile seizures are one of the most common diseases that physicians encounter in pediatric emergency departments. Two important aspects of managing patients presenting with a febrile seizure are meningitis exclusion and co-infection investigation. This study was designed to determine any infection that occurs concomitantly with a febrile seizure episode and also to assess the frequency of meningitis among children presenting with febrile seizures. Methods This retrospective cross-sectional study was conducted at the Children’s Medical Center, an Iranian pediatric referral hospital. All patients aged 6 months to 5 years presenting with febrile seizures from 2020 to 2021 were included. Patients’ data were collected from the medical report files. The presence of respiratory, gastrointestinal, and urinary infections was evaluated. Moreover, the detection of SARS-CoV-2 using reverse transcription polymerase chain reaction (RT-PCR) was performed for suspicious cases. The results of urine and stool analysis, as well as blood, urine, and stool cultures were checked. The frequency of lumbar puncture (LP) performance and its results were studied. The relationship between white blood cells (WBC), erythrocyte sedimentation rate (ESR), and C-reactive protein in meningitis was evaluated. Results A total of 290 patients were referred to the Children’s Medical Center, Tehran, Iran, due to fever and seizures. The mean age of the patients was 21.5 ± 13.0 months, and 134 (46.2%) were female. Out of 290 patients, 17% presented with respiratory infections. Nasopharyngeal SARS-CoV-2 RT-PCR was requested for 50 patients (17%), of which nine (3%) were reported positive and two patients had multi-inflammatory syndrome in children (MIS-C). Fever without local signs, gastroenteritis, and urinary tract infections were found in 40%, 19%, and 14% of the patients, respectively. LP was requested for 97 participants (33.4%) to evaluate central nervous system infection, of which 22 cases were suggestive of aseptic meningitis. Among laboratory tests, leukocytosis was significantly related to aseptic meningitis (odds ratio = 11.1, 95% CI = 3.0- 41.5). The blood culture testing result was positive in seven patients; all of them were due to skin contamination. Conclusion Evaluation of patients for possible meningitis is necessary for febrile seizure management. Although the prevalence of bacterial meningitis in these patients is not high, according to this study and other studies conducted in Iran, aseptic meningitis, especially after Measles, Mumps, and Rubella (MMR) vaccination should be considered. Leukocytosis and increased CRP can predict the occurrence of aseptic meningitis in these patients. However, further studies with a larger sample size are highly recommended. Moreover, during the COVID-19 pandemic, it is recommended to pay attention to an acute COVID-19 infection or evidence of MIS-C in children with fever and seizure.

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Meningitis aséptica por virus parotídeo asociada a la vacuna

Abstract: Los autores declaran no tener conflictos de interés para esta publicación. Sin financiamiento.

Cited by 5 publications

References 9 publications

Aseptic meningitis rare complication of mumps in an adult

Aseptic meningitis rare complication of mumps in an adult

Aseptic meningitis following AZD1222 COVID-19 vaccination

Evaluation of patients presenting with febrile seizures in an Iranian referral hospital: emphasis on the frequency of meningitis and co-infections

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