Meningitis

Swanson, Douglas

doi:10.1542/pir.36-12-514

Cited by 42 publications

(67 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Brain herniation occurred before LP in 11% of the cases which is against the risk of LP (Joffe, 2007). LP does not necessarily have to be the main cause, but may accelerate the process in the patient who ran the risk of herniation (Joffe, 2007;Swanson, 2015;Radetsky, 2014). Brain CT scan cannot totally rule out increased intracranial pressure (ICP).…”

Section: Discussionmentioning

confidence: 99%

“…Acute bacterial meningitis is a serious infection with a significant risk of a CNS sequel or mortality (Joffe, 2007;Swanson, 2015). Brain herniation is a known complication of acute bacterial meningitis (Joffe, 2007;Swanson, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Brain herniation is a known complication of acute bacterial meningitis (Joffe, 2007;Swanson, 2015). The most severe type of bacterial meningitis is fulminant meningitis (FM) (Radetsky, 2014).…”

Section: Introductionmentioning

confidence: 99%

“…The most severe type of bacterial meningitis is fulminant meningitis (FM) (Radetsky, 2014). Computed tomography (CT) is requested to rule out increased intracranial pressure before the lumbar puncture (LP) (Swanson, 2015). There is no clear guideline about the indications of CT before LP in pediatric; there are different protocols for adults varying in accordance with the conservation (April, Long, & Koyfman, 2017;Glimåker, Sjölin, Åkesson, & Naucler, 2017).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Acute Bacterial Meningitis Complicated by Brain Herniation Shortly after Lumbar Puncture: A Case Report

Noaim

2018

GJHS

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Acute Bacterial Meningitis Complicated by Brain Herniation Shortly after Lumbar Puncture: A Case Report

Noaim

2018

GJHS

View full text Add to dashboard Cite

show abstract

“…The usual CSF findings are white blood cell count of 1000 to 5000/ µL with the percentage of neutrophils usually greater than 80%, protein > 200 mg/dL, and glucose < 40 mg/ dL. However, there have been reports shown in multiple studies where bacterial meningitis has no CSF abnormalities [8,9].…”

Section: Case Reportmentioning

confidence: 99%

Streptococcus salivarius Meningitis in Immunocompetent: A Case Report

M¹,

S²,

M³

2018

Int Arch Med Microbiol

View full text Add to dashboard Cite

Streptococcus salivarius (S. salivarius) is a rare cause of purulent meningitis. We report a case of meningitis due to S. salivarius in 15-years-old Sudanese boy. Diagnosis was established based on Cerebrospinal fluid (CSF) findings. The patient responded well to systemic antibiotics and recovered completely without any neurological complications after proper supportive measures. In this patient the meningitis caused by S. salivarius was thought to be spontaneous. The importance of bacteriological diagnosis and proper antibiotic treatment for S. salivarius meningitis is discussed. KeywordsStreptococcus salivarius, Meningitis, Immunocompetent, Cerebrospinal fluid is a Joint commission international (JCI) accredited, with a history of high grade of fever 2 days ago, intermittent, relieved by paracetamol, severe headache and generalized fatigability. On day of admission, he developed one episode of tonic clonic convulsion at home and three times in emergency room. He was intubated and admitted in ICU.Assessment of vital signs on presentation revealed a temperature of 39.2 °C, pulse of 112 beats per minute, and blood pressure of 88/50 mmHg. The physical examination revealed that the patient was toxic, and irritable. Cardiovascular and respiratory systems were normal. Laboratory investigations revealed hemoglobin 13.4 g/dl, total leukocyte count 26.400 cells per cubic millimeter. Liver and renal function, serum electrolytes, calcium and magnesium were within normal limits.The patient have no history of epidural anesthesia, spinal myelography, post-traumatic cerebrospinal fluid leaks, brain abscesses, pericranial fistulas or other procedures associated with S. salivarius contamination and also have no recent contact with meningitis patients.In view of suspected central nervous system infection, lumbar puncture was done. Cerebrospinal fluid (CSF) analysis showed an elevated protein level of 169 mg/dl (reference range, 15 to 45) and decrease glucose concentration of 5.8 mg/dl (reference range of 40 to 70 mg/dl). Gram stain of CSF showed no bacteria, but white blood cells were increased 16 cells/cm, with 56% neutrophils and 44% lymphocytes. With the conclusion of pyogenic meningitis, patient was started on intravenous ceftriaxone (2 gm/12 h), vancomycin (1 gm/12 h)

show abstract

Histopathological changes to the peripheral vestibular system following meningitic labyrinthitis

Pauna

Knoll

Lubner

et al. 2020

Laryngoscope Investig Oto

View full text Add to dashboard Cite

Objective: While cochlear ossification is a common sequela of meningitic labyrinthitis, less is known about the effects of meningitis on the peripheral vestibular end organs. Herein, we investigate histopathologic changes in the peripheral vestibular system and cochlea in patients with a history of meningitic labyrinthitis. Methods: Temporal bone (TB) specimens from patients with a history of meningitis were evaluated and compared to age-matched controls. Specimens were evaluated by light microscopy and assessed for qualitative changes, including the presence of vestibular and/or cochlear endolymphatic hydrops, presence and location of inflammatory cells, new bone formation, and labyrinthitis ossificans; and quantitative changes, including Scarpa's ganglion neuron (ScGN) and spiral ganglion neuron (SGN) counts.Results: Fifteen TBs from 10 individuals met inclusion and exclusion criteria. Presence of inflammatory cells and fibrous tissue was found in 5 TBs. Of these, evidence of labyrinthitis ossificans was found in 2 TBs. In the peripheral vestibular system, mild to severe degeneration of the vestibular membranous labyrinth was identified in 60% of cases (n = 9 TBs). There was a 21.2% decrease (range, 3%-64%) in the mean total count of ScGN in patients with meningitis, compared to age-matched controls. In the cochlea, there was a 45% decrease (range, 25.3%-80.9%) in the mean total count of SGN compared to age-matched controls (n = 14 TBs). Conclusions: Otopathologic analysis of TBs from patients with a history of meningitic labyrinthitis demonstrated distinct peripheral vestibular changes. Future research may help to delineate potential mechanisms for the observed otopathologic changes following meningitis. Level of Evidence: N/A K E Y W O R D S meningitis, otopathology, Scarpa ganglion neurons, spiral ganglion neurons, temporal bone, vestibular changes

show abstract

Meningitis

Cited by 42 publications

References 17 publications

Acute Bacterial Meningitis Complicated by Brain Herniation Shortly after Lumbar Puncture: A Case Report

Acute Bacterial Meningitis Complicated by Brain Herniation Shortly after Lumbar Puncture: A Case Report

Streptococcus salivarius Meningitis in Immunocompetent: A Case Report

Histopathological changes to the peripheral vestibular system following meningitic labyrinthitis

Contact Info

Product

Resources

About