2013
DOI: 10.1590/s1679-45082013000400020 View full text |Buy / Rent full text
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Abstract: With the decline in the rate of infections caused by Haemophilus influenzae serotype b since the widespread vaccination, non-b serotypes should be considered as potential pathogenic agents in children with invasive disease younger than 5 years old. We report the case of an immunocompetent 1-year-old boy with Haemophilus influenzae type f meningitis. The agent was identified in cerebrospinal fluid and blood cultures. Serotyping was performed by tests using polyclonal sera and confirmed by polymerase chain react… Show more

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“…Transfection of p100 or p52 coupled with RANKL stimulation abolished this impairment. Overexpression of RelB also abolished these changes in another aly/aly model (40). The RANKL-controlled osteoprotegerin (OPG) system has been shown to be dysregulated in UC and CD patients, and is correlated with increased bone loss in patient sub-groups (41).…”
Section: Starting the Engine: Non-canonical Nf-κb Stimulatory Ligandsmentioning
“…We report a case of a 12-month-old, immunocompetent female that presented with Haemophilus influenza type f meningitis and a clinical course complicated by bilateral subdural empyemas, central venous thrombosis, and bilateral sensorineural hearing loss. Her initial presentation was significant for viral infection positive for adenovirus and recent history of bilateral acute otitis media which may have predisposed her to colonization and infection [6, 7]. Apart from sensorineural hearing loss, these complications have not been reported in the literature for Haemophilus influenzae type f [8, 9] and should be considered in the care of these patients despite clinical appearance given the severity of complications and potential for acute decompensation.…”
Section: Discussionmentioning
“…Therefore, in the face of the gradual increase of Hif infections, further continuous monitoring of invasive Hi diseases is certainly required. 1 , 2 , 4 …”
Section: Discussionmentioning
“…At the same time, invasive infections caused by NTHi, H. influenzae serotype f (Hif) and other serotypes have been reported more frequently. 1 , 2 Mostly they have occurred among toddlers, older people and patients with coexisting comorbidities, fatal outcomes have been relatively rare. 1 , 3 , 4 , 5 …”
Section: Introductionmentioning